MORPHOMETRIC ANALYSIS OF PAP SMEARS AND CERVICAL BIOPSIES.

Background: In women malignant lesions of the cervix are the most frequent cause of mortality and morbidity and cervical cancer is the third most common cause of cancer deaths worldwide.Cervical cancer incidence is progressively reducing due to the routine use of Pap smears and cervical biopsy. Aim of the study is to use Image Morphometric Software in order to create macro-images to analyze a large number of cells at a given time. A one Methods: year retrospective study was conducted in the Department of Pathology, Dr PSIMS & RF and data pertaining to all pap smears and their corresponding biopsies were reviewed. Each case was analysed with respect to age, and symptoms of the patient. A total of 30 patients aged bet Results: ween 35 and 70 years for whom both cervical biopsy and pap smears were done were studied over a period of 1 year. Based on Age, Symptoms, both pap smears and cervical biopsies were taken and studied . Among the biopsies studied 60% were diagnosed as Chronic Cervicitis aged between 35 to 45 years, distribution of lesions include : Endocervical Polyp (20%) aged between 45 to 50 years, Moderate Dysplasia (10%) aged between 55 to 60 years, Moderately differentiated Squamous Cell Carcinoma (10%) aged between 60 to 70 years. Among pap smears 60% inammatory smears, 20% polypoidal endocervicitis, 10% ASCUS, 10% LSIL. Testing cervical epithelium by Pap smear is a very si Conclusion: mple useful, economical and safe tool for early detection of premalignant and malignant cervical lesions. Gold standard is histopathological examination. The correlation studies are very important tools that can be used in the quality assurance of cytology laboratories.