Chem.Dept./ College of Education Ibn-Al-Haithem University of Baghdad.

  This work includes synthesis a series of some new derivatives of triazine from reaction between the sulfur amino acid (L-cysteine) and different  aldehydes in dry ethanol to obtain thiazolidine ring as diastereo isomers (Cis and Trans)- 2- alkylthiazolidine-4- carboxylic acids (1).     The thiazolidine derivatives (1) suffered  esterfication reaction of carboxylic acid   in presence of  drops of  concentrated sulfuric acid as  a catalyst to give the esters : ethyl  2- alkylthiazolidine -4 - carboxylates (2), which reacted with hydrazine hydrate  in (addition- elimination) reaction to give acid hydrazides : 2-alkylthiazolidine-4-carbohydrazides (3). Acid  hydrazides (3) were reacted with  acetyl chloride by (NH)  acetylation reaction to form:  3- acetyl-2-alkylthiazolidine -4 - carbohydrazides (4).    The last step includes cyclization reaction of compound (4) to yeild triazine-1-one derivatives (5), which undergo  tautomerization  phenomena: triazine -1- ol (6). Triazine derivatives were expected to be biologically active.