Amyloids and protein aggregation

BackgroundProtein Misfolding Disorders (PMDs) are a group of diseases where at least one protein or peptide misfold, aggregates into amyloid‐like structures and accumulates in tiss...

AbstractAlthough the precise cause of Alzheimer's disease is not known, the β‐amyloid peptide chains of 40–42 amino acids are suspected to contribute to the disease. The β‐amyloid ...

IntroductionThe protein C anticoagulant pathway plays a critical role in the negative regulation of the blood clotting response. The pathway is triggered by thrombin, which allows ...

Abstract The progress towards understanding the molecular basis of Alzheimers’s disease is strongly connected to elucidating the early aggregatio...

: Self-attachment of proteins leading to the formation of highly insoluble protein oligomers and aggregates has become an important focus of research owing to its diverse implicati...

Alzheimer’s and Parkinson’s are the two best-known neurodegenerative diseases. Each is associated with the excessive aggregation in the brain and elsewhere of its own characteristi...

Platelet aggregation is one of the important mechanisms in hemostasis. Improper platelet function may lead to bleeding or atherothrombosis. Angelica dahurica (AD) has been used in ...

Solubility is a requirement for many cellular processes. Loss of solubility and aggregation can lead to the partial or complete abrogation of protein function. Thus, understanding ...