Figure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Figure S7, Figure S8, Table S1, Supplementary Materials and Methods from S-Nitrosylation of cIAP1 Switches Cancer Cell Fate from TNFα/TNFR1-Mediated Cell Survival to Cell Death

<p>This file contains: Figure S1: Apoptosis determined by annexin V-FITC/7-AAD. Figure S2: NO prevents TNFa-induced classical NF-kB signaling pathway. Figure S3: Detection of S-nitrosylation of cIAP1 with the biotin-switch assay. Figure S4: Example of MALDI-TOF-MS spectra of S-nitrosylated cIAP1. Figure S5: SW480 stable cell line expressing 6myc-cIAP1-C571/574H. Figure S6: Characterization of apoptosis induced by GTN/TNFa. Figure S7: Functional analysis of the ubiquitin E3 ligase activity of cIAP1 mutants. Figure S8: NO prevents TNFa-mediated complex I to promote complex II. Table S1: TNFa concentration in media from human macrophages treated with 5-Fluorouracil/oxaliplatin. Supplementary Materials and Methods.</p>