Review on Pharmacological Evaluation of Anti-Inflammatory Agents

Anti - inflammatory diseases and pain are among the main problems that significantly influence the lifestyle of millions of people and existing therapies are not always effective and can cause several adverse effects. In this context, the molecular modifications or synthesis of compounds continue being the best strategies for the identification of new compounds for the treatment of pain and inflammation. The aim of this study was to evaluate the anti-inflammatory activities The clinical phase further validated the drug's efficacy in reducing symptoms of inflammatory disorders, including arthritis and soft tissue injuries. Its tolerability and multi-target action position it as a promising alternative to existing therapies. This evaluation supports the potential of the drug for clinical use, offering a new avenue for managing inflammation with reduced side effects. Future studies will focus on long-term safety and broader therapeutic applications.Safety assessments indicated minimal adverse effects at therapeutic doses, with a superior gastrointestinal and cardiovascular safety profile compared to traditional NSAIDs.Compare the efficacy and safety of the agent with standard anti-inflammatory drugs (e.g., NSAIDs, corticosteroids, or biologics). Test the drug in models of acute and chronic inflammation to assess its versatility. Investigate its therapeutic efficacy in specific inflammatory conditions, such as arthritis, colitis, or other autoimmune disorders.Anti-inflammatory drugs, including non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids, are widely used for managing pain, inflammation, and chronic conditions such as arthritis. While effective, their use is associated with significant adverse effects, such as gastrointestinal, cardiovascular, renal, and hepatic toxicities, as well as allergic reactions. Pharmacovigilance, the science and activities involved in detecting, assessing, understanding, and preventing adverse drug reactions (ADRs), plays a critical role in ensuring the safe use of these medications