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Therapeutic Effect of Diminazene Aceturate on Parasitic Blood Fluke Schistosoma mansoni Infection
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Praziquantel is currently the only drug available to treat schistosomiasis, a disease of enormous public health significance caused by a blood fluke of the genus
Schistosoma
. Diminazene, a drug approved by the FDA, has been successfully used to treat diseases caused by blood protozoan parasites. In this study, we evaluated the antiparasitic properties of diminazene against
Schistosoma mansoni
ex vivo
and in mice harboring either chronic or early
S. mansoni
infections.
Title: Therapeutic Effect of Diminazene Aceturate on Parasitic Blood Fluke Schistosoma mansoni Infection
Description:
Praziquantel is currently the only drug available to treat schistosomiasis, a disease of enormous public health significance caused by a blood fluke of the genus
Schistosoma
.
Diminazene, a drug approved by the FDA, has been successfully used to treat diseases caused by blood protozoan parasites.
In this study, we evaluated the antiparasitic properties of diminazene against
Schistosoma mansoni
ex vivo
and in mice harboring either chronic or early
S.
mansoni
infections.
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