Efficacy Of Kokila Varti Anjana In Comparison With Ilaneer Kuzhampu Anjana In Immature Senile Cataract- A Randomized Control Trial.

ABSTRACT According to WHO, globally cataract has remained the major cause of blindness over the years. In India prevalence of blindness was reported to be 8% in the age group of more than 50 years as per the National Blindness survey. Cataract accounts for 62.6% of all blindness affecting 9-12 million bilaterally blind person. To date, effective medical treatment for senile cataracts has not been found. The only treatment of choice is surgery. Considering the increased incidence rate of senile cataracts, unavailability of effective medical measures, possible complications, and contraindications of surgery, the need arises to research the drugs that could effectively help to arrest the progression and disintegration of lens protein. The symptoms of senile cataracts can be related to the stages of kaphaja Timira, Kacha and linganasha. A previous study on Ilaneer kuzhampu Anjana revealed 47% result in immature senile cataracts. To date, there is no study been conducted to reveal the efficacy of Kokila Varti. Hence the efficacy of Kokila varti Anjana in comparison with Ilaneer Kuzhambu Anjana is evaluated in the management of immature senile cataracts. Methodology: - A Randomized control trial with 90 subjects in the age group 0f 50-70 years were selected based on inclusion and exclusion criteria was divided into trial and control groups. Group A (Trial) patients were treated with Kokila Varti Anjana and group B (Control) were treated with Ilaneer Kuzhambu Anjanaa for 4 months. The signs and symptoms of the subjects were assessed on the 0th day, 30th day, 60th day and 90th day, and 120th day. Data was collected and recorded in a structured case proforma and were statistically analyzed. Result: The effect of kokila varti Anjana was more in cortical and posterior subcapsular cataracts and the effect of ilaneer kuzhambu Anjana was more in the nuclear type of cataract considering the relief in the signs and symptoms over the study period with statistical analysis and significance of p- value. Conclusion: Within the limitation of the study, it is concluded that both Kokila varti Anjana and Ilaneer kuzhmbu Anjana are effective in immature senile cataracts. The effect of kokila varti Anjana is more in cortical and posterior subcapsular cataracts and the effect of ilaneer kuzhambu Anjana is more in the nuclear type of cataract. Clinical assessment revealed that the study was effective in preventing the progression of immature senile cataracts.