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The Synthesis of 2-substituted Benzo[b]furans Catalyzed by Ni/5-Bromo- 2,2’-bipyridine

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Abstract: A tandem system that enabled the synthesis of 2-substituted benzo[b]furans from 2- halophenols and aryl acetylenes catalyzed by Ni/5-bromo-2,2’-dipyridine was explored. The protocol was found effective for one-pot cascade coupling cyclization reaction producing benzo[b]furan compounds, and heteroaryl substrates were observed to be compatible for this system as well, giving corresponding products in 20-70% yields.
Title: The Synthesis of 2-substituted Benzo[b]furans Catalyzed by Ni/5-Bromo- 2,2’-bipyridine
Description:
Abstract: A tandem system that enabled the synthesis of 2-substituted benzo[b]furans from 2- halophenols and aryl acetylenes catalyzed by Ni/5-bromo-2,2’-dipyridine was explored.
The protocol was found effective for one-pot cascade coupling cyclization reaction producing benzo[b]furan compounds, and heteroaryl substrates were observed to be compatible for this system as well, giving corresponding products in 20-70% yields.

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