Review Article: Fish Bone Collagen

Fishbone collagen is an alternative source of bovine and pig collagen. The purpose of this article is to review the types, benefits, extraction methods and characterization of collagen from fish bones, especially freshwater fish. The result of the review shows that the collagen from tilapia bones is shaped like a sheet with a slight porous surface and is of type I. Collagen extraction begins with bone disease from the remaining fat, then degreasing and the next step is extraction. After the extraction process is complete, filtration is carried out to store the filtrate or residue, then the collagen is purified by salting-out with NaCl. Collagen yield and collagen pH value from collagen extraction were different for each type of fish bone. The difference in yield value and protein and amino acid content in the resulting collagen can be caused by differences in the extraction method, the concentration of the solution used, whether acid or alkaline, and the neutralization process and the type of raw material. Fishbone collagen has good benefits in the cosmetic and pharmaceutical fields.