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Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases
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Ewing sarcoma is an aggressive mesenchymal malignancy. It is the second most common bone tumor among children and adolescents and less commonly presents as a soft tissue or primary skin lesion. Cutaneous Ewing sarcoma has only been reported in case reports and case series. In this article, we describe a 12-year-old Hispanic female cured of localized, cutaneous Ewing sarcoma (pT1aN0M0) at the 40-month follow-up following surgical resection and adjuvant chemotherapy according to the COG AEWS1031 protocol for Ewing sarcoma of the bone. To our knowledge, this is the first article to provide a potential biological explanation for the differences in the prognosis of Ewing sarcoma of the bone, soft tissue, and skin.
Title: Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases
Description:
Ewing sarcoma is an aggressive mesenchymal malignancy.
It is the second most common bone tumor among children and adolescents and less commonly presents as a soft tissue or primary skin lesion.
Cutaneous Ewing sarcoma has only been reported in case reports and case series.
In this article, we describe a 12-year-old Hispanic female cured of localized, cutaneous Ewing sarcoma (pT1aN0M0) at the 40-month follow-up following surgical resection and adjuvant chemotherapy according to the COG AEWS1031 protocol for Ewing sarcoma of the bone.
To our knowledge, this is the first article to provide a potential biological explanation for the differences in the prognosis of Ewing sarcoma of the bone, soft tissue, and skin.
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