Javascript must be enabled to continue!
Renal metastasis of ovarian granulosa cell tumor
View through CrossRef
IntroductionWe would like to present a rare case of metastatic renal tumor.Case presentationA 60‐year‐old woman presented to our department with a left renal tumor. She underwent a total hysterectomy and right adnexal resection for a stage IA ovarian granulosa cell tumor approximately 15 years ago, followed by left adnexal resection and postoperative chemotherapy with gemcitabine and paclitaxel 6 years ago. She received six courses of gemcitabine and carboplatin to treat a stage IC clear cell adenocarcinoma of the ovary.The patient was diagnosed with the left renal tumor and underwent a laparoscopic left nephrectomy. Immunostaining was positive for α‐inhibin and SF‐1 and showed FOXL2 402C→G (C134W) mutation. Finally, the patient was diagnosed with renal metastasis of a granulosa cell tumor.ConclusionTo our knowledge, this is a very rare case of renal metastasis of a granulosa cell tumor with the FOXL2 mutation in an adult.
Title: Renal metastasis of ovarian granulosa cell tumor
Description:
IntroductionWe would like to present a rare case of metastatic renal tumor.
Case presentationA 60‐year‐old woman presented to our department with a left renal tumor.
She underwent a total hysterectomy and right adnexal resection for a stage IA ovarian granulosa cell tumor approximately 15 years ago, followed by left adnexal resection and postoperative chemotherapy with gemcitabine and paclitaxel 6 years ago.
She received six courses of gemcitabine and carboplatin to treat a stage IC clear cell adenocarcinoma of the ovary.
The patient was diagnosed with the left renal tumor and underwent a laparoscopic left nephrectomy.
Immunostaining was positive for α‐inhibin and SF‐1 and showed FOXL2 402C→G (C134W) mutation.
Finally, the patient was diagnosed with renal metastasis of a granulosa cell tumor.
ConclusionTo our knowledge, this is a very rare case of renal metastasis of a granulosa cell tumor with the FOXL2 mutation in an adult.
Related Results
Renal Ewing Sarcoma: A Case Report and Literature Review
Renal Ewing Sarcoma: A Case Report and Literature Review
Abstract
Introduction
Primary renal Ewing sarcoma is an extremely rare and aggressive tumor, representing less than 1% of all renal tumors. This case report contributes valuable in...
The effect of miRNAs and MALAT1 related with the prognosis of Her-2 positive breast cancer patients with lymph node metastasis
The effect of miRNAs and MALAT1 related with the prognosis of Her-2 positive breast cancer patients with lymph node metastasis
Abstract
Background: To analyze and screen the miRNAs associated with lymph node metastasis of breast cancer (BC), and to explore the roles of these miRNAs in the prolifera...
Psychological stress in women with ovarian tumors
Psychological stress in women with ovarian tumors
Objective: To determine the level of psychological stress in women with ovarian tumors. Methods: A crosssectional description of 461 women hospitalized with ovarian tumors at Hue C...
Data from Osteopontin-c Splicing Isoform Contributes to Ovarian Cancer Progression
Data from Osteopontin-c Splicing Isoform Contributes to Ovarian Cancer Progression
<div>Abstract<p>Ovarian carcinoma is one of the most aggressive gynecological diseases and generally diagnosed at advanced stages. Osteopontin (OPN) is one of the prote...
Data from Osteopontin-c Splicing Isoform Contributes to Ovarian Cancer Progression
Data from Osteopontin-c Splicing Isoform Contributes to Ovarian Cancer Progression
<div>Abstract<p>Ovarian carcinoma is one of the most aggressive gynecological diseases and generally diagnosed at advanced stages. Osteopontin (OPN) is one of the prote...
Long noncoding RNA C-Terminal binding protein 1 antisense regulates ovarian granulosa cells proliferation and autophagy and participates in polycystic ovary syndrome
Long noncoding RNA C-Terminal binding protein 1 antisense regulates ovarian granulosa cells proliferation and autophagy and participates in polycystic ovary syndrome
Abstract
Long non-coding RNA (lncRNA) C-Terminal binding protein 1 antisense (CTBP1-AS) was reported that it is associated with polycystic ovarian syndrome (PCOS) in Chines...
Abstract IA31: Molecular epidemiology of ovarian cancer
Abstract IA31: Molecular epidemiology of ovarian cancer
Abstract
Epithelial ovarian cancer (EOC) accounts for 5% of all cancer deaths and is the fifth leading cause of cancer death in women in the United States. While the...
Breast Carcinoma within Fibroadenoma: A Systematic Review
Breast Carcinoma within Fibroadenoma: A Systematic Review
Abstract
Introduction
Fibroadenoma is the most common benign breast lesion; however, it carries a potential risk of malignant transformation. This systematic review provides an ove...

