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Functionalization of Calcium Sulfate/Bioglass Scaffolds with Zinc Oxide Whisker
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There are urgent demands for satisfactory antibacterial activity and mechanical properties of bone scaffolds. In this study, zinc oxide whisker (ZnOw) was introduced into calcium sulfate/bioglass scaffolds. Antimicrobial behavior was analyzed using Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The results showed that the scaffolds presented a strong antibacterial activity after introducing ZnOw, due to the antibacterial factors released from the degradation of ZnO. Moreover, ZnOw was also found to have a distinct reinforcing effect on mechanical properties. This was ascribed to whisker pull-out, crack bridging, crack deflection, crack branching and other toughening mechanisms. In addition, the cell culture experiments showed that the scaffolds with ZnOw had a good biocompatibility.
Title: Functionalization of Calcium Sulfate/Bioglass Scaffolds with Zinc Oxide Whisker
Description:
There are urgent demands for satisfactory antibacterial activity and mechanical properties of bone scaffolds.
In this study, zinc oxide whisker (ZnOw) was introduced into calcium sulfate/bioglass scaffolds.
Antimicrobial behavior was analyzed using Escherichia coli (E.
coli) and Staphylococcus aureus (S.
aureus).
The results showed that the scaffolds presented a strong antibacterial activity after introducing ZnOw, due to the antibacterial factors released from the degradation of ZnO.
Moreover, ZnOw was also found to have a distinct reinforcing effect on mechanical properties.
This was ascribed to whisker pull-out, crack bridging, crack deflection, crack branching and other toughening mechanisms.
In addition, the cell culture experiments showed that the scaffolds with ZnOw had a good biocompatibility.
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