TIME TO LOSS OF CONSCIOUSNESS AND TRACHEAL INTUBATION WITHOUT NEUROMUSCULAR BLOCKADE USING SEVOFLURANE: A COMPARATIVE ANALYSIS OF CLINICAL VERSUS BISPECTRAL INDEX MONITORED DEPTH OF ANAESTHESIA

Endotracheal intubation is the gold standard for airway management that establishes a definitive airway. Because of the problems associated with the use of neuromuscular blockade, BIS monitoring serves as a guide for the adequacy of the depth of anaesthesia for non-paralytic endotracheal intubation. The aim of the study was to compare the time to loss of consciousness and tracheal intubation following induction with sevoflurane without neuromuscular blockade in paediatric patients monitored for depth of anaesthesia either by clinical features or BIS. This study was a randomised, single-blind, controlled clinical trial conducted among 56 children aged 2 to 6 years with ASA of I and II scheduled for elective adenotonsillectomy. They were randomly allocated into two groups to either receive BIS monitoring (group B) or clinical monitoring (group C) of the depth of anaesthesia. A study pro forma was used to record patientsÂ’ time to loss of consciousness and time to tracheal intubation. Data was entered into and analysed by SPSS version 23 with a p-value set at 0.05. The mean time to loss of consciousness from induction to loss of consciousness was 350.04 27.680 seconds in the BIS group and 90.89 19.916 seconds in the clinical group (p=0.012) the mean time to tracheal intubation from laryngoscopy to completion of intubation was 19.29 1.117 seconds and 19.64 1.129 seconds in the BIS and clinical groups, which was not statistically significant with p=0.541.