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Relationship between vacA Types and Development of Gastroduodenal Diseases
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The Helicobacter pylori vacuolating cytotoxin (VacA) is a secreted pore-forming toxin and a major virulence factor in the pathogenesis of H. pylori infection. While VacA is present in almost all strains, only some forms are toxigenic and pathogenic. While vacA and its genotypes are considered as markers of H. pylori-related diseases or disorders, the pathophysiological mechanisms of VacA and its genotypes remain controversial. This review outlines key findings of publications regarding vacA with emphasis on the relationship between vacA genotypes and the development of human disease.
Title: Relationship between vacA Types and Development of Gastroduodenal Diseases
Description:
The Helicobacter pylori vacuolating cytotoxin (VacA) is a secreted pore-forming toxin and a major virulence factor in the pathogenesis of H.
pylori infection.
While VacA is present in almost all strains, only some forms are toxigenic and pathogenic.
While vacA and its genotypes are considered as markers of H.
pylori-related diseases or disorders, the pathophysiological mechanisms of VacA and its genotypes remain controversial.
This review outlines key findings of publications regarding vacA with emphasis on the relationship between vacA genotypes and the development of human disease.
Related Results
Study of the correlation between the vacA genotype of Helicobacter pylori, the VacA product and gastroduodenal disease
Study of the correlation between the vacA genotype of Helicobacter pylori, the VacA product and gastroduodenal disease
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Seismostratigraphic Analysis of the Vaca Muerta Formation in the Veta Escondida-Rincon de Aranda Area, Neuquén Basin
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Abstract
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CagA , VacA and urease can assist in predicting the development trend of chronic gastritis
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Abstract
Background
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Helicobacter pylori vacuolating cytotoxin genotypes and preneoplastic lesions or gastric cancer risk: a meta‐analysis
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As múltiplas características distintas do leite materno e do leite de vaca fazem com que o esvaziamento gástrico seja mais rápido após ingestão do primeiro. Esta rapidez do esvazia...
Systematic treatment of giant gastroduodenal anastomotic leakage：a case report
Systematic treatment of giant gastroduodenal anastomotic leakage：a case report
Abstract
Background
Gastroduodenal anastomotic leakage is one of the most dreadful complications of gastrectomy and poses a great threat for treatment. However, there has ...
Systematic treatment of giant gastroduodenal anastomotic leakage: a case report
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Abstract
Background: Gastroduodenal anastomotic leakage is one of the most dreadful complications of gastrectomy and poses a great threat for treatment. However, there has ...