Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
CD4/CD8 double-negative mycosis fungoides: a review
View through CrossRef
Mycosis Fungoides (MF) stands as the predominant form of primary cutaneous T-cell lymphoma (CTCL). It manifests a diverse array of clinical, histological, and immunophenotypic variations, each bearing distinct prognostic implications. The typical immunophenotypic profile of mycosis fungoides involves CD3+/CD4+/CD45RO+ memory T cells. Notably, the CD4-/CD8- double-negative variant of MF is a rare occurrence, observed in approximately 12% of early-stage cases and more prevalent in tumor-stage instances, often correlated with atypical clinical presentations. Despite its rarity, scant information is available about double-negative Mycosis Fungoides, with only a limited number of cases documented in the existing literature. This review aims to provide enhanced clarity, comprehension, and a detailed exploration of the spectrum encompassing double-negative mycosis fungoides.
PAGEPress Publications
Title: CD4/CD8 double-negative mycosis fungoides: a review
Description:
Mycosis Fungoides (MF) stands as the predominant form of primary cutaneous T-cell lymphoma (CTCL).
It manifests a diverse array of clinical, histological, and immunophenotypic variations, each bearing distinct prognostic implications.
The typical immunophenotypic profile of mycosis fungoides involves CD3+/CD4+/CD45RO+ memory T cells.
Notably, the CD4-/CD8- double-negative variant of MF is a rare occurrence, observed in approximately 12% of early-stage cases and more prevalent in tumor-stage instances, often correlated with atypical clinical presentations.
Despite its rarity, scant information is available about double-negative Mycosis Fungoides, with only a limited number of cases documented in the existing literature.
This review aims to provide enhanced clarity, comprehension, and a detailed exploration of the spectrum encompassing double-negative mycosis fungoides.
Related Results
Thyroid Dysfunction in Mycosis Fungoides: Sonographic and Laboratory Insights
Thyroid Dysfunction in Mycosis Fungoides: Sonographic and Laboratory Insights
Introduction: Thyroid gland affection in mycosis fungoides has been rarely reported. It occurs as extracutaneous involvement, incidentally, as a second malignancy, or as a side eff...
The identification of tumor-infiltrating lymphocytes in patients with stomach cancer
The identification of tumor-infiltrating lymphocytes in patients with stomach cancer
Background. Stomach cancer (SC) is the 6th most common neoplasm among cancers (1 033 701 cases; 5.7%) and the 3rd most deadly cancer worldwide for men and women (782 685 deaths, 8....
Predictors of False-Negative Axillary FNA Among Breast Cancer Patients: A Cross-Sectional Study
Predictors of False-Negative Axillary FNA Among Breast Cancer Patients: A Cross-Sectional Study
Abstract
Introduction
Fine-needle aspiration (FNA) is commonly used to investigate lymphadenopathy of suspected metastatic origin. The current study aims to find the association be...
Abstract 1704: Concurrent expression of PD-1 and TIGIT increased on effector T cells of CLL patients
Abstract 1704: Concurrent expression of PD-1 and TIGIT increased on effector T cells of CLL patients
Abstract
Tumor cells avoid elimination by the host immune system using physiological immune checkpoint pathways. Among various lymphoma subtypes, most non-Hodgkin ly...
The definition and risks of Cytokine Release Syndrome-Like in 11 COVID-19-Infected Pneumonia critically ill patients: Disease Characteristics and Retrospective Analysis
The definition and risks of Cytokine Release Syndrome-Like in 11 COVID-19-Infected Pneumonia critically ill patients: Disease Characteristics and Retrospective Analysis
IMPORTANCECOVID-19-infected pneumonia patients with severe immune abnormalities and risk of cytokine release syndrome. The definition, prevention, and treatment of COVID-19-infecte...
Association Between CD4/CD8 Ratio Recovery and Chronic Kidney Disease Among Human Immunodeficiency Virus-Infected Patients Receiving Antiretroviral Therapy: A 17-Year Observational Cohort Study
Association Between CD4/CD8 Ratio Recovery and Chronic Kidney Disease Among Human Immunodeficiency Virus-Infected Patients Receiving Antiretroviral Therapy: A 17-Year Observational Cohort Study
Background:CD4/CD8 ratio is considered as an emerging biomarker for human immunodeficiency virus (HIV)-related diseases. However, the relationship of CD4/CD8 ratio recovery and chr...
Imbalance between CD8+CD28+ and CD8+CD28– T-cell subsets and its clinical significance in patients with systemic lupus erythematosus
Imbalance between CD8+CD28+ and CD8+CD28– T-cell subsets and its clinical significance in patients with systemic lupus erythematosus
Objective The aim of this study was to evaluate the changes in CD8+CD28–/CD8+CD28+ T-cell subset balance and in the CD8+CD28– Treg cell number and function in patients with systemi...
Hubungan Hitung CD4 dengan Infeksi Cryptosporidium pada Pasien HIV AIDS
Hubungan Hitung CD4 dengan Infeksi Cryptosporidium pada Pasien HIV AIDS
Abstract. Human immunodeficiency virus (HIV) is a virus that can attack CD4 lymphocytes and cause immune cell death, resulting in severe immune deficiency in infected individuals. ...