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Computational modelling of the key stages of placing bioresorbable polymeric coronary stent

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Cardiovascular diseases are one of the main problems in the world in medicine. It ranks first in the list of causes of fatal accidents, in addition, more than a half of cases are a result of ischemic heart diseases. One of the most effective method of treatment is coronary stenting. The main purpose of the study is to outline bioresorbable polymeric coronary stent’s behaviour using computational modelling and to demonstrate benefits of application of polymer materials instead of standard metallic alloys. During the research the main stages of coronary stenting that are necessary for general understanding of process were analyzed: the strain after crimping, the shape of angioplasty balloon after deployment and the stress-strain state of vessel and atherosclerotic plaque after coronary stent deployment. PLLA (poly-L-lactic acid) was taken as a material for the research. It allows to create stent construction that will provide the required lumen of the vessel during rehabilitation. Moreover, with the progress of poly-L-lactic acid vasomotor function will restore thereby forming «golden section». The results showed the possibility of use of approaches that were given in this paper for examination of polymer material’s behaviour with coronary stenting. It can be concluded that polymer bioresorbable coronary stents in medicine are promising for further application for improvement of quality of invasive coronary operation.
Title: Computational modelling of the key stages of placing bioresorbable polymeric coronary stent
Description:
Cardiovascular diseases are one of the main problems in the world in medicine.
It ranks first in the list of causes of fatal accidents, in addition, more than a half of cases are a result of ischemic heart diseases.
One of the most effective method of treatment is coronary stenting.
The main purpose of the study is to outline bioresorbable polymeric coronary stent’s behaviour using computational modelling and to demonstrate benefits of application of polymer materials instead of standard metallic alloys.
During the research the main stages of coronary stenting that are necessary for general understanding of process were analyzed: the strain after crimping, the shape of angioplasty balloon after deployment and the stress-strain state of vessel and atherosclerotic plaque after coronary stent deployment.
PLLA (poly-L-lactic acid) was taken as a material for the research.
It allows to create stent construction that will provide the required lumen of the vessel during rehabilitation.
Moreover, with the progress of poly-L-lactic acid vasomotor function will restore thereby forming «golden section».
The results showed the possibility of use of approaches that were given in this paper for examination of polymer material’s behaviour with coronary stenting.
It can be concluded that polymer bioresorbable coronary stents in medicine are promising for further application for improvement of quality of invasive coronary operation.

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