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Behavioral Teratogenesis of Heavy Metals: Problems in Experimental Research*
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Abstract Lead and methylmercury are environmental hazards known to have deleterious effects on the development of fetuses. In the recent decades, increasing concern has been expressed over the behavioral teratogenesis of these heavy metals. The present paper discusses some of the methodological problems in investigating the mechanisms of behavioral teratogenesis of lead and methylmercury; i.e., 1) metabolism of the substances in pregnant animals, together with fetal and neonatal exposure, 2) ages of offspring to be examined, and 3) selection of behavioral measures. Perspectives on dose‐effect relationships of behavioral teratology of these heavy metals are provided, by reviewing selected papers concerning behavioral teratology of lead and methylmercury.
Title: Behavioral Teratogenesis of Heavy Metals: Problems in Experimental Research*
Description:
Abstract Lead and methylmercury are environmental hazards known to have deleterious effects on the development of fetuses.
In the recent decades, increasing concern has been expressed over the behavioral teratogenesis of these heavy metals.
The present paper discusses some of the methodological problems in investigating the mechanisms of behavioral teratogenesis of lead and methylmercury; i.
e.
, 1) metabolism of the substances in pregnant animals, together with fetal and neonatal exposure, 2) ages of offspring to be examined, and 3) selection of behavioral measures.
Perspectives on dose‐effect relationships of behavioral teratology of these heavy metals are provided, by reviewing selected papers concerning behavioral teratology of lead and methylmercury.
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