Acceptability and Usability of Colli-Pee UAS for First Void Urine Self Sampling

First-void urine as sample type has shown great potential for cancer detection, screening and monitoring. It is an emerging liquid biopsy with broad applicability in different analytes and cancers. The aim of this feasibility study was to investigate the experiences of healthy and diseased cohorts of first-void urine collection and preservation using the Colli-Pee® UAS™ devices (Novosanis NV), both for collection during doctors visit as well as home-sampling. Questionnaires from 98 participants enrolled in the URODETECT studies were analyzed. Participants reported that Colli-Pee® was clear (90%) and comfortable (68%) to use. Most respondents (82%) rated their general experience of Colli-Pee® as easy to very easy, while only 2% indicated it was difficult. Participants also reported their intention to use Colli-Pee® again (87%) or to recommend Colli-Pee® to their friends and/or family (88%). A subset of participants (n=60) collected urine samples at home using Colli-Pee® UAS™ devices and returned their samples to the laboratory. Most participants’ responses were positive (very easy, 35%, easy 40%) about the entire self-sampling process. Urine collection, at home or in the clinic, using Colli-Pee® was clearly accepted by all participants. Furthermore, self-sampling could offer the possibility to increase at home cancer screening coverage and provide more comfort for individuals.