Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Quorum Sensing Inhibitory Potential and Molecular Docking Studies of Phyllanthus Emblica Phytochemicals Against Pseudomonas Aeruginosae
View through CrossRef
Abstract
Phyllanthus emblica a traditional medicinal plant that is endowed with curative properties including anti-bacterial, anti-fungal, anti-viral, and analgesic properties. Bacteria make use of cell–cell signaling system known as Quorum sensing (QS) and respond to their own population. In most gram-negative bacteria, the transcriptional regulators belonging to the Lux R protein play a crucial role in the QS mechanism by detecting the presence of signaling molecules known as N-acyl homoserine lactones (AHLs). In this present work, the anti-quorum sensing activity of Phyllanthus emblica was evaluated against Pseudomonas aeruginosa. Anti-quorum sensing efficacy of Phyllanthus emblica was estimated with reference to QS Bio-monitoring strain Chromobacterium violaceum. The binding efficacy of the phytochemicals of Phyllanthus emblica against CviR Protein from Chromobacterium violaceum and LasR Protein from Phyllanthus emblica were studied.
Springer Science and Business Media LLC
Title: Quorum Sensing Inhibitory Potential and Molecular Docking Studies of Phyllanthus Emblica Phytochemicals Against Pseudomonas Aeruginosae
Description:
Abstract
Phyllanthus emblica a traditional medicinal plant that is endowed with curative properties including anti-bacterial, anti-fungal, anti-viral, and analgesic properties.
Bacteria make use of cell–cell signaling system known as Quorum sensing (QS) and respond to their own population.
In most gram-negative bacteria, the transcriptional regulators belonging to the Lux R protein play a crucial role in the QS mechanism by detecting the presence of signaling molecules known as N-acyl homoserine lactones (AHLs).
In this present work, the anti-quorum sensing activity of Phyllanthus emblica was evaluated against Pseudomonas aeruginosa.
Anti-quorum sensing efficacy of Phyllanthus emblica was estimated with reference to QS Bio-monitoring strain Chromobacterium violaceum.
The binding efficacy of the phytochemicals of Phyllanthus emblica against CviR Protein from Chromobacterium violaceum and LasR Protein from Phyllanthus emblica were studied.
Related Results
Bacterial LomR Induces the Vibriophage VP882 VqmA-Directed Quorum-Sensing Lysogeny-Lysis Transition
Bacterial LomR Induces the Vibriophage VP882 VqmA-Directed Quorum-Sensing Lysogeny-Lysis Transition
SUMMARY
The bacterial cell-cell communication process called quorum sensing enables groups of bacteria to synchronously alter behavior in respons...
Cloning, purification, and enzymatic activity of the quorum sensing signal synthase RhlI
Cloning, purification, and enzymatic activity of the quorum sensing signal synthase RhlI
Quorum sensing is a bacterial cell‐cell communication system that functions through the synthesis, secretion, and detection of signaling molecules called autoinducers. Quorum sensi...
Formulation development of chewable tablets containing Phyllanthus emblica Linn. fruit extract by direct compression
Formulation development of chewable tablets containing Phyllanthus emblica Linn. fruit extract by direct compression
Indian gooseberry (Phyllanthus emblica Linn.), a plant in family Euphobiaceae, is a tree growing in tropical parts of Southeast Asia. Its fruits have been widely used in folk medic...
DTMol: Pocket-based Molecular Docking using Diffusion Transformers
DTMol: Pocket-based Molecular Docking using Diffusion Transformers
Abstract
In computational chemistry, molecular docking—predicting the binding structure of a small molecule ligand to a protein—is vital for understanding interacti...
Hierarchical transcriptional regulation of quorum-sensing genes inVibrio harveyi
Hierarchical transcriptional regulation of quorum-sensing genes inVibrio harveyi
AbstractIn vibrios, quorum sensing controls hundreds of genes that are required for cell density-specific behaviors including bioluminescence, biofilm formation, competence, secret...
Formulation and evaluation of herbal ointment using Emblica officinalis extract
Formulation and evaluation of herbal ointment using Emblica officinalis extract
Herbal medicine prepare various part of plant are used like flower, leaves, seeds, root etc. Instead off an herbal drug is design as the alternative formulation for the external u...
Exploring Phytochemical Compounds Against Pseudomonas Aeruginosa Using QSAR, Molecular Dynamics, and Free Energy Landscape
Exploring Phytochemical Compounds Against Pseudomonas Aeruginosa Using QSAR, Molecular Dynamics, and Free Energy Landscape
AbstractPseudomonas aeruginosa is a versatile opportunistic bacterium that presents a considerable risk in medical environments because of its strong adaptability and resistance to...
Pseudomonas Species Prevalence, Protein Analysis, and Antibiotic Resistance: An Evolving Public Health Challenge
Pseudomonas Species Prevalence, Protein Analysis, and Antibiotic Resistance: An Evolving Public Health Challenge
Abstract
Psychrotrophic Pseudomonas is one of the significant microbes that lead to putrefaction in chilled meat. One of the biggest problems in the detection of Pseudomona...