Javascript must be enabled to continue!
Atypical Presentation of Gout: Idiopathic Retrocalcaneal Pain in 400 Patients
View through CrossRef
Introduction: Idiopathic retrocalcaneal pain is frequently linked to overuse injuries or inflammation around the Achilles tendon and surrounding bursae. However, systemic conditions such as gout, characterized by monosodium urate crystal deposition, can also present as retrocalcaneal pain. Gout commonly affects the first metatarsophalangeal joint, but atypical presentations like retrocalcaneal involvement are increasingly recognized. This study aims to assess the presentation, diagnosis, and treatment outcomes of gout in patients presenting with idiopathic retrocalcaneal pain.
Materials and Methods: This retrospective study analysed clinical data from 400 patients diagnosed with gout and presenting with idiopathic retrocalcaneal pain between 2019 and 2023 at a tertiary care centre. Diagnosis was based on clinical examination, serum uric acid levels, imaging, and in some cases, synovial fluid analysis. Patient demographics, diagnostic methods, and treatment outcomes, including pain (VAS) and functionality (FADI) scores, were evaluated.
Results: Of the 400 patients, 290 (72.5%) were male, and 110 (27.5%) were female, with a mean age of 56.8 ± 12.3 years. Pre-existing gout was present in 58% of patients, and serum uric acid levels were elevated in 75%. Synovial fluid analysis, performed in 65 patients, confirmed monosodium urate crystals in 92.3% of cases. Treatment resulted in significant reductions in pain (VAS: 7.8 ± 1.4 to 3.2 ± 1.1, p < 0.05) and improved functionality (FADI: 58.4 ± 5.7 to 85.7 ± 6.3). Recurrence of symptoms occurred in 25% of patients, particularly in those who did not adhere to urate-lowering therapy.
Conclusion: This study emphasizes the importance of considering gout in the differential diagnosis of idiopathic retrocalcaneal pain. Early diagnosis and appropriate management can lead to favourable outcomes and lower recurrence rates. Clinicians should remain vigilant for atypical presentations of gout to prevent prolonged discomfort and functional impairment.
Keywords: Idiopathic retrocalcaneal pain, gout, hyperuricemia, monosodium urate crystals, Achilles tendon, atypical gout, urate-lowering therapy
Indian Orthopaedic Research Group
Title: Atypical Presentation of Gout: Idiopathic Retrocalcaneal Pain in 400 Patients
Description:
Introduction: Idiopathic retrocalcaneal pain is frequently linked to overuse injuries or inflammation around the Achilles tendon and surrounding bursae.
However, systemic conditions such as gout, characterized by monosodium urate crystal deposition, can also present as retrocalcaneal pain.
Gout commonly affects the first metatarsophalangeal joint, but atypical presentations like retrocalcaneal involvement are increasingly recognized.
This study aims to assess the presentation, diagnosis, and treatment outcomes of gout in patients presenting with idiopathic retrocalcaneal pain.
Materials and Methods: This retrospective study analysed clinical data from 400 patients diagnosed with gout and presenting with idiopathic retrocalcaneal pain between 2019 and 2023 at a tertiary care centre.
Diagnosis was based on clinical examination, serum uric acid levels, imaging, and in some cases, synovial fluid analysis.
Patient demographics, diagnostic methods, and treatment outcomes, including pain (VAS) and functionality (FADI) scores, were evaluated.
Results: Of the 400 patients, 290 (72.
5%) were male, and 110 (27.
5%) were female, with a mean age of 56.
8 ± 12.
3 years.
Pre-existing gout was present in 58% of patients, and serum uric acid levels were elevated in 75%.
Synovial fluid analysis, performed in 65 patients, confirmed monosodium urate crystals in 92.
3% of cases.
Treatment resulted in significant reductions in pain (VAS: 7.
8 ± 1.
4 to 3.
2 ± 1.
1, p < 0.
05) and improved functionality (FADI: 58.
4 ± 5.
7 to 85.
7 ± 6.
3).
Recurrence of symptoms occurred in 25% of patients, particularly in those who did not adhere to urate-lowering therapy.
Conclusion: This study emphasizes the importance of considering gout in the differential diagnosis of idiopathic retrocalcaneal pain.
Early diagnosis and appropriate management can lead to favourable outcomes and lower recurrence rates.
Clinicians should remain vigilant for atypical presentations of gout to prevent prolonged discomfort and functional impairment.
Keywords: Idiopathic retrocalcaneal pain, gout, hyperuricemia, monosodium urate crystals, Achilles tendon, atypical gout, urate-lowering therapy.
Related Results
Frequency of Common Chromosomal Abnormalities in Patients with Idiopathic Acquired Aplastic Anemia
Frequency of Common Chromosomal Abnormalities in Patients with Idiopathic Acquired Aplastic Anemia
Objective: To determine the frequency of common chromosomal aberrations in local population idiopathic determine the frequency of common chromosomal aberrations in local population...
Cometary Physics Laboratory: spectrophotometric experiments
Cometary Physics Laboratory: spectrophotometric experiments
<p><strong><span dir="ltr" role="presentation">1. Introduction</span></strong&...
Differential Diagnosis of Neurogenic Thoracic Outlet Syndrome: A Review
Differential Diagnosis of Neurogenic Thoracic Outlet Syndrome: A Review
Abstract
Thoracic outlet syndrome (TOS) is a complex and often overlooked condition caused by the compression of neurovascular structures as they pass through the thoracic outlet. ...
Increased Metallothionein-1 associated with gout activity and tophi
Increased Metallothionein-1 associated with gout activity and tophi
Abstract
Introduction:Gout is a chronic self-limiting inflammatory arthritis. The mechanism for the spontaneous rapid resolution of inflammation in acute gout was not yet t...
Hypertension and gout: A Mendelian randomization study
Hypertension and gout: A Mendelian randomization study
Abstract
Background: Although there is solid epidemiological evidence supporting the connection between hypertension and gout, the causal relationship and direction associa...
Gout therapy updated
Gout therapy updated
Gout is a common and painful inflammatory arthritis caused by monosodium urate crystal deposition into joints in the setting of hyperuricemia. Recent reports indicate an increase i...
OA28 Really... gout?! An unexpected diagnosis of gout in the wrist of a 12-year-old girl
OA28 Really... gout?! An unexpected diagnosis of gout in the wrist of a 12-year-old girl
Abstract
Introduction
Gout is a common form of inflammatory arthritis in adults but is rare in children and adolescents. ...
Chest Wall Hydatid Cysts: A Systematic Review
Chest Wall Hydatid Cysts: A Systematic Review
Abstract
Introduction
Given the rarity of chest wall hydatid disease, information on this condition is primarily drawn from case reports. Hence, this study systematically reviews t...

