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Ketofol as induction agent in diabetic patients.
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Objective: To evaluate the role of ketofol as induction agent in diabetic patients. Study Design: Randomized Control Trial. Setting: Department of Anesthesia, Abwa Medical College, Faisalabad. Period: 01-12-21 to 01-05-22. Material & Methods: Patients after informed consent divided randomly into two groups 25 in each. Group A receiving propofol 1.5 mg/kg and Group B receiving ketofol 1:2 as induction agent. The dose given was 1ml for every 5Kg. Standard 5 parameter monitoring with pulse oximetry, ECG, non invasive BP done starting from preoperative to 2 minutes, 5 minutes and 10 minutes after induction agent given. MAP and HR were monitored. Hemodynamic instability was defined as I) Heart rate >160/min or <50/min. II) MAP>120mmHg or <60 mm Hg. Results: Total 50 patients included in this study. 25 in each group. The results show significant stability in hemodynamics in group B. Conclusion: Ketofol has better hemodynamic stability as induction agent in diabetic patients when used in a 2:1 ratio. This makes it a good choice for this specific patient population.
Independent Medical Trust
Title: Ketofol as induction agent in diabetic patients.
Description:
Objective: To evaluate the role of ketofol as induction agent in diabetic patients.
Study Design: Randomized Control Trial.
Setting: Department of Anesthesia, Abwa Medical College, Faisalabad.
Period: 01-12-21 to 01-05-22.
Material & Methods: Patients after informed consent divided randomly into two groups 25 in each.
Group A receiving propofol 1.
5 mg/kg and Group B receiving ketofol 1:2 as induction agent.
The dose given was 1ml for every 5Kg.
Standard 5 parameter monitoring with pulse oximetry, ECG, non invasive BP done starting from preoperative to 2 minutes, 5 minutes and 10 minutes after induction agent given.
MAP and HR were monitored.
Hemodynamic instability was defined as I) Heart rate >160/min or <50/min.
II) MAP>120mmHg or <60 mm Hg.
Results: Total 50 patients included in this study.
25 in each group.
The results show significant stability in hemodynamics in group B.
Conclusion: Ketofol has better hemodynamic stability as induction agent in diabetic patients when used in a 2:1 ratio.
This makes it a good choice for this specific patient population.
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