Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Archaea: an archetype for replication initiation studies?
View through CrossRef
SummaryWhereas the process of DNA replication is fundamentally conserved in the three domains of life, the archaeal system is closer to that of eukarya than bacteria. In the time since the complete genome sequences of several members of the archaeal domain became available, there has been a burst of research on archaeal DNA replication. These studies have led to both expected and surprising findings. This review summarizes the search for origins of replication in archaea, and our current knowledge of initiation, the process by which replication origins are recognized, the DNA molecule is unwound and the replicative helicase is loaded onto the DNA in preparation for DNA synthesis. The similarities and differences of the initiation process in archea, bacteria and eukarya are also summarized.
Title: Archaea: an archetype for replication initiation studies?
Description:
SummaryWhereas the process of DNA replication is fundamentally conserved in the three domains of life, the archaeal system is closer to that of eukarya than bacteria.
In the time since the complete genome sequences of several members of the archaeal domain became available, there has been a burst of research on archaeal DNA replication.
These studies have led to both expected and surprising findings.
This review summarizes the search for origins of replication in archaea, and our current knowledge of initiation, the process by which replication origins are recognized, the DNA molecule is unwound and the replicative helicase is loaded onto the DNA in preparation for DNA synthesis.
The similarities and differences of the initiation process in archea, bacteria and eukarya are also summarized.
Related Results
Single‐Molecule Optical Replication Mapping (ORM) Suggests Human Replication Timing is Regulated by Stochastic Initiation
Single‐Molecule Optical Replication Mapping (ORM) Suggests Human Replication Timing is Regulated by Stochastic Initiation
DNA replication timing is regulated by the timing of initiation across the genome. However, there is no consensus as to how initiation timing is regulated. Deterministic models con...
Identification of 1600 replication origins in S. cerevisiae
Identification of 1600 replication origins in S. cerevisiae
Abstract
There are approximately 500 known origins of replication in the yeast genome, and the process by which DNA replication initiates at these locations is well understood. In ...
Systematic genome-guided discovery of antagonistic interactions between archaea and bacteria
Systematic genome-guided discovery of antagonistic interactions between archaea and bacteria
ABSTRACTThe social life of archaea is poorly understood. In particular, even though competition and conflict are common themes in microbial communities, there is scant evidence doc...
Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis
Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis
ABSTRACT
Similar to other positive-strand RNA viruses, hepatitis C virus (HCV) causes massive rearrangements of intracellular membranes, resulting in a membranous web (MW...
Abstract 1841: Characterizing long non-coding RNAs located within a replication origin at the human DBF4 locus.
Abstract 1841: Characterizing long non-coding RNAs located within a replication origin at the human DBF4 locus.
Abstract
Faithful replication of the entire genome only once per cell cycle is crucial to cell homeostasis. The importance of proper replication is manifested by the...
Identification of 1600 replication origins in S. cerevisiae
Identification of 1600 replication origins in S. cerevisiae
Abstract
There are approximately 500 known origins of replication in the yeast genome, and the process by which DNA replication initiates at these locations is well understood. In ...
DNA replication
DNA replication
This chapter evaluates DNA replication, which occurs in three distinct phases: initiation, elongation, and termination. Initiation of replication in bacteria occurs at a unique chr...