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FORMULATE AND EVALUATE GEL CONTAINING NANOSTRUCTURED LIPIDS OF PONGAMIA PINNATA
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The objective of present study was to design development and evaluatenanostructure lipid carriers based gel of Pongamia pinnata extract for topical application. Nanostructured lipid carriers (NLC) established topical gel of Pongamia pinnata extract was formulated for treatment of wound healing activity, NLC were fabricated by melt dispersion ultra-sonication method. NLC containing mixtures of Glyceryl monostearate as solid lipid and Karanj Oil as liquid- lipid and the Tween 80 as surfactant. The particle size of NLC was found between 99.98 and 155.65 nm with PDI varied from 0.256 to 0.349 and zeta potential found between -21.65 to -26.68. The NLC dispersions were gelled by utilizing gelling agent carbopol which have compatibility with nano-particulate dispersion.. From stability study it revealed that formulation is stable and used for topical application
Title: FORMULATE AND EVALUATE GEL CONTAINING NANOSTRUCTURED LIPIDS OF PONGAMIA PINNATA
Description:
The objective of present study was to design development and evaluatenanostructure lipid carriers based gel of Pongamia pinnata extract for topical application.
Nanostructured lipid carriers (NLC) established topical gel of Pongamia pinnata extract was formulated for treatment of wound healing activity, NLC were fabricated by melt dispersion ultra-sonication method.
NLC containing mixtures of Glyceryl monostearate as solid lipid and Karanj Oil as liquid- lipid and the Tween 80 as surfactant.
The particle size of NLC was found between 99.
98 and 155.
65 nm with PDI varied from 0.
256 to 0.
349 and zeta potential found between -21.
65 to -26.
68.
The NLC dispersions were gelled by utilizing gelling agent carbopol which have compatibility with nano-particulate dispersion.
From stability study it revealed that formulation is stable and used for topical application.
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