Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Hepatic collagenolytic activity in rats after carbon tetrachloride poisoning
View through CrossRef
1. Collagenolytic activity towards acid-soluble collagen labelled with [14C]-proline was assayed in rat liver with and without carbon tetrachloride poisoning. The products of enzymic digestion were found to be free amino acids and peptides. 2. The hepatic collagenolytic activity increased under conditions of single-dose and subacute carbon tetrachloride poisoning, and correlated with hydroxyproline content. The highest activity was found during recovery from subacute poisoning. 3. Under the same experimental conditions, hepatic acid-proteinase activity changed independently of the collagenolytic activity and also of hepatic hydroxyproline content. 4. The increased collagenolytic activity during carbon tetrachloride poisoning was found mainly in the supernatant fraction. 5. The ratio of the collagenolytic activity to hepatic hydroxyproline content increased during recovery from single-dose and subacute poisoning, and decreased during subacute poisoning.
Title: Hepatic collagenolytic activity in rats after carbon tetrachloride poisoning
Description:
1.
Collagenolytic activity towards acid-soluble collagen labelled with [14C]-proline was assayed in rat liver with and without carbon tetrachloride poisoning.
The products of enzymic digestion were found to be free amino acids and peptides.
2.
The hepatic collagenolytic activity increased under conditions of single-dose and subacute carbon tetrachloride poisoning, and correlated with hydroxyproline content.
The highest activity was found during recovery from subacute poisoning.
3.
Under the same experimental conditions, hepatic acid-proteinase activity changed independently of the collagenolytic activity and also of hepatic hydroxyproline content.
4.
The increased collagenolytic activity during carbon tetrachloride poisoning was found mainly in the supernatant fraction.
5.
The ratio of the collagenolytic activity to hepatic hydroxyproline content increased during recovery from single-dose and subacute poisoning, and decreased during subacute poisoning.
Related Results
Evidence against Pathway-Selective Hepatic Insulin Resistance in Mice
Evidence against Pathway-Selective Hepatic Insulin Resistance in Mice
Insulin suppresses hepatic glucose production and increases hepatic de novo lipogenesis (DNL). Paradoxically, hepatic DNL remains elevated in insulin-resistant subjects, leading to...
PO-238 Urinary metabolomics study on the anti-depression effect of different exercise modes on CUMS model rats
PO-238 Urinary metabolomics study on the anti-depression effect of different exercise modes on CUMS model rats
Objective To study the effects of different exercise modes on CUMS depression model rats by 1H-NMR metabolomics technique, and to explore the mechanism of exercise anti-depression ...
PO-217 Plasma metabolomics study on the anti-depression effect of different exercise modes on CUMS model rats
PO-217 Plasma metabolomics study on the anti-depression effect of different exercise modes on CUMS model rats
Objective Objective: To study the anti-depression effect of different modes of exercise on CUMS rats and explore the mechanism by 1 H-NMR metabonomics methods.
Methods Method...
The Effects of Succimer and Penicillamine on Acute Lead Poisoning Patients
The Effects of Succimer and Penicillamine on Acute Lead Poisoning Patients
Background: Lead poisoning was on the rise in recent years. There exists a lack of easy access to some of the main chelator drugs in developing countries. Thus, this study aimed to...
Electrocardiogram Changes in Patients With Acute Ethanol Poisoning
Electrocardiogram Changes in Patients With Acute Ethanol Poisoning
Background: Alcohol consumption leads to a significant number of deaths, mostly in men, worldwide. Considering the effect of ethanol toxicity on the heart, we studied various Elect...
The Subcutaneous Injection of Organophosphate: A Case Report
The Subcutaneous Injection of Organophosphate: A Case Report
Organophosphate (OP) poisoning is prevalent in developing countries. Toxicity occurs by voluntary injection, inhalation, and absorption. Self-injection is rare. The current case re...
HRTEM of Initial Oxidation of Carbon Nanotube Tips
HRTEM of Initial Oxidation of Carbon Nanotube Tips
Abstract
High resolution transmission electron microscopy (HRTEM) and diffraction technique, with their high sensitivity to small variations in periodic structure or...
RNA profiles of rat olfactory epithelia: individual and age related variations
RNA profiles of rat olfactory epithelia: individual and age related variations
Abstract
Background
Mammalian genomes contain a large number (~1000) of olfactory receptor (OR) genes, many of which (20 to 50%) are pseudogenes....
Recent Results
The Electromagnetic Spectrum: Knowledge and Experimental Techniques
The Electromagnetic Spectrum: Knowledge and Experimental Techniques
The electromagnetic spectrum classifies and explores the properties of electromagnetic radiation. This classification does not contradict the concept of wave and particle, only the...
Your session has timed out for security reasons.