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Long-term outcomes of concomitant tricuspid valve repair in patients undergoing mitral valve surgery

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Abstract Background We aimed to find out how the concomitant performance of tricuspid valve repair (TVR) affects outcomes of patients undergoing mitral valve surgery (MVS). Methods Single-centre, retrospective analysis of 1357 patients who underwent MVS between January 2005 and December 2015, including 1165 patients with isolated MVS and 192 patients with MVS plus TVR. We used propensity scores to match patients for baseline characteristics other than valve related parameters and arrived at a matched sample of 182 patients per group. Results The overall procedure duration was longer in the MVS + TVR (224 min) versus the MVS group (176 min; p < 0.001), as were the duration of mechanical ventilation (13 vs. 11 h; p < 0.001), X-clamp (90.5 vs. 66 min; p < 0.001) and cardiopulmonary bypass time (136 vs. 95.5 min; p < 0.001). Rates of procedural complications were not different between groups with the exception of pacemaker rates which were 16.0% in the MVS + TVR group and 8.8% in the isolated MVS group (p = 0.037). There was no difference in death rates within 30 days, stroke, myocardial infarction or repeat MVS. The long-term survival rate was 60.8% in the MVS + TVR vs. 57.5% in the isolated MVS group (HR 1.048; 95%CI 0.737–1.492; p = 0.794). The rate of grade III/IV tricuspid regurgitation (TR) remained low after MVS + TVR during long-term follow-up while the rate of grade ≥ II TR increased slightly in the isolated MVS group. Conclusion The data show that the concomitant performance of TVR in patients undergoing MVS is a safe and effective procedure with good long-term outcomes. Patients can undergo MVS + TVR with confidence as it improves their prognosis up to the level of patients undergoing isolated MVS.
Title: Long-term outcomes of concomitant tricuspid valve repair in patients undergoing mitral valve surgery
Description:
Abstract Background We aimed to find out how the concomitant performance of tricuspid valve repair (TVR) affects outcomes of patients undergoing mitral valve surgery (MVS).
Methods Single-centre, retrospective analysis of 1357 patients who underwent MVS between January 2005 and December 2015, including 1165 patients with isolated MVS and 192 patients with MVS plus TVR.
We used propensity scores to match patients for baseline characteristics other than valve related parameters and arrived at a matched sample of 182 patients per group.
Results The overall procedure duration was longer in the MVS + TVR (224 min) versus the MVS group (176 min; p < 0.
001), as were the duration of mechanical ventilation (13 vs.
11 h; p < 0.
001), X-clamp (90.
5 vs.
66 min; p < 0.
001) and cardiopulmonary bypass time (136 vs.
95.
5 min; p < 0.
001).
Rates of procedural complications were not different between groups with the exception of pacemaker rates which were 16.
0% in the MVS + TVR group and 8.
8% in the isolated MVS group (p = 0.
037).
There was no difference in death rates within 30 days, stroke, myocardial infarction or repeat MVS.
The long-term survival rate was 60.
8% in the MVS + TVR vs.
57.
5% in the isolated MVS group (HR 1.
048; 95%CI 0.
737–1.
492; p = 0.
794).
The rate of grade III/IV tricuspid regurgitation (TR) remained low after MVS + TVR during long-term follow-up while the rate of grade ≥ II TR increased slightly in the isolated MVS group.
Conclusion The data show that the concomitant performance of TVR in patients undergoing MVS is a safe and effective procedure with good long-term outcomes.
Patients can undergo MVS + TVR with confidence as it improves their prognosis up to the level of patients undergoing isolated MVS.

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