Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
ANTIBODIES IN THE PIG AGAINST PIG INSULIN
View through CrossRef
ABSTRACT
Sera from three pigs injected subcutaneously with respectively pig, ox, and horse insulin for 87 days were incubated with 131I-pig insulin and investigated for the presence of antibodies by means of immunoelectrophoresis and autoradiography.
A binding of 131I-pig insulin to the gamma globulin fraction could be demonstrated in all animals after the commencement of the injections. Thus a cross reactivity between pig and ox insulin and pig and horse insulin occurred, however, apparently to a lesser degree in the latter case. The presence of a 131I-pig insulin binding gamma fraction in the serum from the animal injected with pig insulin, indicates a formation of antibodies against pig insulin in the pig.
Title: ANTIBODIES IN THE PIG AGAINST PIG INSULIN
Description:
ABSTRACT
Sera from three pigs injected subcutaneously with respectively pig, ox, and horse insulin for 87 days were incubated with 131I-pig insulin and investigated for the presence of antibodies by means of immunoelectrophoresis and autoradiography.
A binding of 131I-pig insulin to the gamma globulin fraction could be demonstrated in all animals after the commencement of the injections.
Thus a cross reactivity between pig and ox insulin and pig and horse insulin occurred, however, apparently to a lesser degree in the latter case.
The presence of a 131I-pig insulin binding gamma fraction in the serum from the animal injected with pig insulin, indicates a formation of antibodies against pig insulin in the pig.
Related Results
Pregnancy and Challenging Transient Anti-GAD65 Positivity: A Case Report with Literature Review
Pregnancy and Challenging Transient Anti-GAD65 Positivity: A Case Report with Literature Review
Abstract
Introduction
During pregnancy, women may develop blood glucose abnormalities like gestational diabetes mellitus (GDM) or, rarely, type 1 diabetes (T1D), which can lead to ...
New and simple Ohmic definition of insulin resistance in lean and obese subjects
New and simple Ohmic definition of insulin resistance in lean and obese subjects
objective:: Insulin enhances the influx of glucose into cells. However, the relationship between glucose and insulin is complex and insulin sensitivity varies widely with age, ethn...
Insulin Lispro: Its Role in the Treatment of Diabetes Mellitus
Insulin Lispro: Its Role in the Treatment of Diabetes Mellitus
OBJECTIVE:
To introduce a rapid-acting human insulin analog, insulin lispro; to review its pharmacology, therapeutics, pharmacokinetics, dosing guidelines, adve...
Mutations in Insulin-Receptor Gene in Insulin-Resistant Patients
Mutations in Insulin-Receptor Gene in Insulin-Resistant Patients
Defects in insulin-receptor function have been associated with insulin-resistant states such as obesity and non-insulin-dependent diabetes mellitus (NIDDM). Several types of mutati...
Effect of intranasal insulin on osteocalcin levels and postoperative delirium in elderly patients undergoing joint replacement
Effect of intranasal insulin on osteocalcin levels and postoperative delirium in elderly patients undergoing joint replacement
Abstract
Background
Recently, intranasal insulin has shown great promise in preventing perioperative neurocognitive disorders t...
A Case of Insulin Resistance Secondary to Insulin Induced Localized Cutaneous Amyloidosis.
A Case of Insulin Resistance Secondary to Insulin Induced Localized Cutaneous Amyloidosis.
Abstract
Abstract 4908
Insulin resistance can be a major problem in patients with diabetes mellitus. Although multiple reasons can result in this prob...
Pu'aka Tonga
Pu'aka Tonga
I have only ever owned one pig. It didn’t have a name, due as it was for the table. Just pu‘aka. But I liked feeding it; nothing from the household was wasted. I planned not to bec...
Partial Characterization of Mechanism of Insulin Accumulation in H35 Hepatoma Cell Nuclei
Partial Characterization of Mechanism of Insulin Accumulation in H35 Hepatoma Cell Nuclei
The mechanism controlling insulin accumulation in nuclei of H35 hepatoma cells was investigated by incubating intact cells with 125|-labeled insulin in the presence or absence of a...