THE EFFECT OF BODY MASS INDEX, AND VITAMIN D LEVEL ON ACNE IN FEMALE PATIENTS IN MISURATA CITY

Acne is a chronic inflammatory disease that affects the pilosebaceous unit, it isconsidered as one of the most common skin diseases worldwide, especially amongadolescent population. The pathogenesis of acne is largely multifactorial and is still notfully understood. In contrast to our knowledge of the genetic and hormonal role in thepathogenesis of acne, there is uncertainty regarding other factors, including diet, bodymass index and vitamin D. Studies of the role of these factors in the pathogenesis ofacne have shown conflicting and inconclusive results. This study aimed to know theeffect of body mass index, and vitamin D level on acne vulgaris, and their associationwith acne severity through a representative sample of female acne patients in Misratacity. A prospective study, a total of 129 acne vulgaris female patients and 47 matchedhealthy subjects as controls have been enrolled in this study. To collect data a self-madequestionnaire was designed. The collected data was statistically analyzed usingStatistical Package for the Social Sciences (SPSS) version 28. According to this study,vitamin D level influences the presence of acne (p-value= 0.001) however it does notaffect its severity (p-value= 0.348). No correlation was found between acne and thebody mass index (p-value was 0.701). This study found that a deficient vitamin D levelaffect acne vulgaris in female patients, and may play a potential role in pathogenesis ofacne vulgaris but no correlation between acne and the body mass index.