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Superficial Spreading Melanoma with a Nodular Area: Antigenic Phenotype of the Radial and Vertical Growth Areas

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We investigated antigenic features associated with different tumor progression steps in primary melanoma, interpreted as different patterns of growth (radial and vertical) in the same and in different lesions. Thirty-eight primary melanomas were examined: 18 superficial spreading malanomas, 13 superficial spreading melanomas with a nodular area and 7 nodular melanomas. 225.28,763.74, CL.203, VF19LL209, VF19LL217, Q5.13, W6.32 and anti-HLA-DR monoclonal antibodies were used. Phenotypic differences between radial and vertical growth areas were observed but no statistical significance could be found.
Title: Superficial Spreading Melanoma with a Nodular Area: Antigenic Phenotype of the Radial and Vertical Growth Areas
Description:
We investigated antigenic features associated with different tumor progression steps in primary melanoma, interpreted as different patterns of growth (radial and vertical) in the same and in different lesions.
Thirty-eight primary melanomas were examined: 18 superficial spreading malanomas, 13 superficial spreading melanomas with a nodular area and 7 nodular melanomas.
225.
28,763.
74, CL.
203, VF19LL209, VF19LL217, Q5.
13, W6.
32 and anti-HLA-DR monoclonal antibodies were used.
Phenotypic differences between radial and vertical growth areas were observed but no statistical significance could be found.

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