Cat-Scratch disease manifesting as uveitis and binocular fundus nodular lesions: a case report

Abstract Background Cat-scratch disease usually manifests with uveitis, vitritis, retinitis, retinochoroiditis and optic neuritis, yet, with fundus nodular lesions rarely reported. In our study, we report a case of Cat-Scratch disease with binocular fundus nodular lesions. Case presentation An 11-year old male presented with uveitis (right eye) and binocular fundus nodular lesions after indirect contact with unvaccinated cats. Ancillary examinations (Wide-angle fundus photography, Ultrasonography, Fluorescein fundus angiography, Optical coherence tomography and Orbital Magnetic Resonance Imaging) were conducted to describe the multidimensional features of the binocular lesions. Metagenomics next-generation sequencing confirmed the diagnosis of Cat-scratch disease. The patient’s condition improved after 6-month combination treatment of systemical doxycycline hyclat and methylprednisolone tablets plus local mydriatic and corticosteroid eye drops. Conclusions We firstly reported a case simultaneously combined with uveitis and binocular fundus nodular lesions secondary to infection of Bartonella henselae in a child. Timely diagnosis and treatment with antibiotics and corticosteroids could improve the prognosis of these disorders.