Age and Cervical flexorshelp diagnosedegenerative cervical myelopathy

Abstract Objective: To evaluate the relationship betweenage and cervical paraspinal muscles (PSM) and degenerative cervical myelopathy (DCM);to establish a diagnostic model for degenerative cervical myelopathy (DCM)with age and Cervical flexors.Methods: A retrospective cohort study of 100 patients with DCM taken at The First Affiliated Hospital of Guangxi Medical University and Wuzhou Red Cross Hospitalbetween December 2018 and June 2020 was performed.C2-C7 Cobb's angle,disc degeneration,endplate degeneration,fatty infiltration and morphology of paraspinal muscles (PSMs)were measured.Receiver operating characteristic (ROC) curves were established to evaluate the value of diagnostic methods. Fisher’s discriminant model was taken to establish a diagnostic model for DCM. Kappa value was calculated to compare different diagnostic models.Results: The multivariate analysis results showed that age and cervical flexors were potential risk factors for DCM.The ability to diagnose DCM alone and in combination using ROC curve method was assessed, showing that the combination of the two indicators had the best diagnostic effect. Fisher's discriminant was used to establish a diagnostic model. Using leave-one-out cross-validation,the diagnostic equation was got:y1=0.33x1+10.302x2-24.139; y2=0.259x1+13.605x2-32.579. Comparison of this diagnostic model and other diagnostic toolsshowed that this diagnostic model performed better (sensitivity 66.7%, specificity 81.3%, accuracy 72.5%), Kappa value 0.363, p=0.011.Conclusion: Age and cervical flexors were potential risk factors for DCM.In this study, a diagnostic model for the diagnosis of DCM was developed using Fisher's discriminant method, combining age and cervical flexors.