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Stereotypical depiction of Erdheim-Chester Disease on Tc-99m MDP skeletal scintigraphy
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Erdheim-Chester Disease (ECD) is a rare systemic histiocytic disorder characterized by symmetrical skeletal involvementand variable visceral manifestations. Tc-99m MDP bone scintigraphy, CT, MRI, and FDG PET-CT are essential for diagnosisand disease mapping. ECD’s course depends on extraosseous involvement, with potential complications including heartand renal failure. We present the case of ECD with bilateral leg pain and orbital involvement. Imaging revealed mixed scleroticand lytic skeletal lesions, cerebellar lesions, intraorbital soft tissue masses, mediastinal and retroperitoneal infiltration.Keywords: Erdheim-Chester Disease (ECD), Skeletal and Visceral Involvement, Tc-99m MDP Bone Scintigraphy
Pakistan Medical Association
Title: Stereotypical depiction of Erdheim-Chester Disease on Tc-99m MDP skeletal scintigraphy
Description:
Erdheim-Chester Disease (ECD) is a rare systemic histiocytic disorder characterized by symmetrical skeletal involvementand variable visceral manifestations.
Tc-99m MDP bone scintigraphy, CT, MRI, and FDG PET-CT are essential for diagnosisand disease mapping.
ECD’s course depends on extraosseous involvement, with potential complications including heartand renal failure.
We present the case of ECD with bilateral leg pain and orbital involvement.
Imaging revealed mixed scleroticand lytic skeletal lesions, cerebellar lesions, intraorbital soft tissue masses, mediastinal and retroperitoneal infiltration.
Keywords: Erdheim-Chester Disease (ECD), Skeletal and Visceral Involvement, Tc-99m MDP Bone Scintigraphy.
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