Antimicrobial activity of Various Sulfone Derivatives: A Review

Sulfones are the organo sulfur compounds containing sulfonyl functional group attached to two carbon atoms. Sulfone derivatives have wide range of biological and pharmacological properties. Due to the wide range of applications chemistry of sulfones has been explored. Most of the sulfone analogues are studied for their antimicrobial activity. The use of drugs containing sulfones extends from the treatment of chronic and acute Gram-positive and Gram - negative bacterial infections, through malaria, trachoma, leprosy, dermatitis herpetiformis, pneumocystis carinii pneumonia (PCP), nocardiosis, coccidiosis to toxoplasmosis. The present review includes rigorous literature survey on the sulfone derivatives as an antimicrobial agent and offer prospective in the development of new sulfone derivative as antimicrobial agent.