Glomus Tumour of Sciatic Nerve – A Rare Presentation Mimicking Sciatica

Introduction: Nerve tumors are rare entities with variable presentation from pain, numbness, burning, to variable motor deficits. The most common nerve tumors are Schwannoma and Neurofibroma, which arise from the nerve sheath. Rarely tumor arises from the epineural tissue of the nerve, such as hemangioma, engiometosis, paraganglioma, lipoma, and glomus tumor. Case Report: We are reporting an extremely rare case of Glomus tumor in a 48-year-old female from the most proximal part of the sciatic nerve extending from the L4-5 region in the retroperitoneal space inside the pelvis to the extra-pelvic region up to inferior gluteal fold. Surgery was performed and a partial excision and decompression were performed. The patient had good pain relief after surgery. Conclusion: The case highlights the importance of clinical findings, early detection, and multidisciplinary management of Nerve tumor to optimize patient outcomes. To our knowledge, this is the only case of glomus tumor involving the proximal part of the sciatic nerve with intrapelvic and extrapelvic extension reported in the literature. Keywords: Glomus tumor, sciatic nerve, sciatica, nerve, spine, endoscopy.