Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Case of nivolumab-induced sclerosing cholangitis: lessons from long-term follow-up
View through CrossRef
Nivolumab is an immune checkpoint inhibitor used to treat multiple solid-organ malignancies. While many of its immune-related adverse events are well established, nivolumab-induced sclerosing cholangitis remains poorly characterised, with no defined diagnostic criteria. Moreover, data regarding long-term outcomes are particularly lacking. We present a biopsy-proven case of nivolumab-induced sclerosing cholangitis, which uniquely captures 18 months of follow-up post-treatment. Our case highlights key features of intrahepatic subtype sclerosing cholangitis and suggests durable response to corticosteroid therapy.
Title: Case of nivolumab-induced sclerosing cholangitis: lessons from long-term follow-up
Description:
Nivolumab is an immune checkpoint inhibitor used to treat multiple solid-organ malignancies.
While many of its immune-related adverse events are well established, nivolumab-induced sclerosing cholangitis remains poorly characterised, with no defined diagnostic criteria.
Moreover, data regarding long-term outcomes are particularly lacking.
We present a biopsy-proven case of nivolumab-induced sclerosing cholangitis, which uniquely captures 18 months of follow-up post-treatment.
Our case highlights key features of intrahepatic subtype sclerosing cholangitis and suggests durable response to corticosteroid therapy.
Related Results
Hydatid Disease of The Brain Parenchyma: A Systematic Review
Hydatid Disease of The Brain Parenchyma: A Systematic Review
Abstarct
Introduction
Isolated brain hydatid disease (BHD) is an extremely rare form of echinococcosis. A prompt and timely diagnosis is a crucial step in disease management. This ...
Clinical Criteria and Operative Complications of Complicated Cholangitis
Clinical Criteria and Operative Complications of Complicated Cholangitis
Introduction: Complicated cholangitis is a severe bacterial infection of the bile ducts that often occurs in patients with biliary obstruction. The condition is characterized by a ...
Association between antibiotic exposure and survival in patients with hepatocellular carcinoma treated with nivolumab.
Association between antibiotic exposure and survival in patients with hepatocellular carcinoma treated with nivolumab.
e16186 Background: Nivolumab, an immune checkpoint inhibitor, has improved the outcomes of patients with hepatocellular carcinoma (HCC). It is approved for HCC patients previously...
Breast Carcinoma within Fibroadenoma: A Systematic Review
Breast Carcinoma within Fibroadenoma: A Systematic Review
Abstract
Introduction
Fibroadenoma is the most common benign breast lesion; however, it carries a potential risk of malignant transformation. This systematic review provides an ove...
IgG4-Related Sclerosing Cholangitis Mimicking Cholangiocarcinoma
IgG4-Related Sclerosing Cholangitis Mimicking Cholangiocarcinoma
IgG4-related sclerosing cholangitis (IgG4-SC) is a relatively newly identified disease that is frequently associated with autoimmune pancreatitis. The differential diagnosis betwee...
Evaluation of cardiac adverse events with nivolumab using a Japanese real-world database
Evaluation of cardiac adverse events with nivolumab using a Japanese real-world database
Abstract
The present study aimed to determine the risk of nivolumab-induced cardiac adverse events (AEs), time to onset, incidence rates, and post hoc outcomes using the Ja...
Role of Serum Procalcitonin in Prediction of Severity in Patients with Acute Cholangitis
Role of Serum Procalcitonin in Prediction of Severity in Patients with Acute Cholangitis
Abstract
Background Cholangitis is one of the commonest emergencies encountered by gastroenterologists that may warrant drainage of biliary system. Serum procalcitonin (P...
Real-world data of second-line immunotherapy in metastatic clear cell renal cell carcinoma
Real-world data of second-line immunotherapy in metastatic clear cell renal cell carcinoma
Background:
Targeted therapies have prolonged the survival of patients with metastatic renal cell carcinomas (RCC). However, the majority of patients with metastatic RC...