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Kinetic Modeling
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The quantification of perfusion from arterial spin labeling (ASL) perfusion MRI data relies upon the principles of tracer kinetics. This chapter first outlines the simplest form of a tracer kinetic model that can be applied to ASL data, before exploring variations on this model that can be applied to extract other hemodynamic information such as arterial transit time. Finally, the chapter examines how tracer kinetic models are used with data to estimate perfusion parameters, including the use of model fitting and Bayesian inference.
Oxford University Press
Title: Kinetic Modeling
Description:
The quantification of perfusion from arterial spin labeling (ASL) perfusion MRI data relies upon the principles of tracer kinetics.
This chapter first outlines the simplest form of a tracer kinetic model that can be applied to ASL data, before exploring variations on this model that can be applied to extract other hemodynamic information such as arterial transit time.
Finally, the chapter examines how tracer kinetic models are used with data to estimate perfusion parameters, including the use of model fitting and Bayesian inference.
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