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Inherent directing group-enabled Co(iii)-catalyzed C–H allylation/vinylation of isoquinolones
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Isoquinolones undergo efficient Co(iii)-catalyzed C8-allylation and vinylation, utilizing the oxo group of isoquinolones as an inherent directing group. The resulting allylated and vinylated isoquinolones are further transformed into important building blocks.
Royal Society of Chemistry (RSC)
Title: Inherent directing group-enabled Co(iii)-catalyzed C–H allylation/vinylation of isoquinolones
Description:
Isoquinolones undergo efficient Co(iii)-catalyzed C8-allylation and vinylation, utilizing the oxo group of isoquinolones as an inherent directing group.
The resulting allylated and vinylated isoquinolones are further transformed into important building blocks.
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