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Ru‐Catalyzed CH Functionalization of Heterocycles

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Abstract Heterocycles are key structural motifs in a variety of organic functional compounds, which are widely used in organic chemistry, pharmaceutical sciences, optoelectronics, and material science. In recent years, direct CH bond activation/functionalization has become a promising and attractive synthetic strategy and has been widely applied to construct new CC and Cheteroatom bonds. This article focuses on recent progress in ruthenium‐catalyzed‐directed CH functionalization of heterocycles, including CH alkylation, alkenylation, and alkynylation. In addition, due to the importance and rapid progress in photocatalysis, pioneering work was also summarized in the field of photoredox CH heterocycles functionalization employing ruthenium as photocatalyst.
Title: Ru‐Catalyzed CH Functionalization of Heterocycles
Description:
Abstract Heterocycles are key structural motifs in a variety of organic functional compounds, which are widely used in organic chemistry, pharmaceutical sciences, optoelectronics, and material science.
In recent years, direct CH bond activation/functionalization has become a promising and attractive synthetic strategy and has been widely applied to construct new CC and Cheteroatom bonds.
This article focuses on recent progress in ruthenium‐catalyzed‐directed CH functionalization of heterocycles, including CH alkylation, alkenylation, and alkynylation.
In addition, due to the importance and rapid progress in photocatalysis, pioneering work was also summarized in the field of photoredox CH heterocycles functionalization employing ruthenium as photocatalyst.

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