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BioEssays 12/2010
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Cover Photograph: Hypothetical structure of the dynamin oligomer. During endocytosis clathrincoated pits and ultimately vesicles are formed at the plasma membrane. The constriction and cleavage of these vesicles is achieved by the action of the GTPase dynamin. On pages 1033–1039 Nikolaus Pawlowski discusses recent findings on the structure and function of dynamin and explains how dynamin oligomers are expected to form and thus participate in vesicle fission. The oligomerisation of two other dynamin superfamily proteins is also briefly addressed. (Structure as suggested by Gao et al., Nature 465: 502‐6.)
Title: BioEssays 12/2010
Description:
Cover Photograph: Hypothetical structure of the dynamin oligomer.
During endocytosis clathrincoated pits and ultimately vesicles are formed at the plasma membrane.
The constriction and cleavage of these vesicles is achieved by the action of the GTPase dynamin.
On pages 1033–1039 Nikolaus Pawlowski discusses recent findings on the structure and function of dynamin and explains how dynamin oligomers are expected to form and thus participate in vesicle fission.
The oligomerisation of two other dynamin superfamily proteins is also briefly addressed.
(Structure as suggested by Gao et al.
, Nature 465: 502‐6.
).
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