Acute Ischemic Stroke and Metabolic Syndrome Comorbidity

Aim Cerebrovascular diseases (CVD) lead to serious disabilities and loss of labor in societyin addition to mortality. Metabolic syndrome (MetS) is a group of known metabolic risk factors such as high blood pressure, dyslipidemia, glucose intolerance, or high blood sugar, due to insulin resistance. The present study aimed to investigate MetS and its components in acute ischemic stroke patients and analyze these components as risk factors. MATERIAL-METHOD The study was conducted with 80 patients, 46 males and 34 females, who were admitted to the Taksim Training and Research Hospital Neurology Clinic with acute ischemic stroke diagnosis between April and October 2007 within the first 48 hours of the disease onset. The presence of MetS was investigated in 80 patients, including large artery atherosclerosis (BAA), small artery occlusion (CAO), and cardioembolic disease (CE). FINDINGS MetS was determined in 48 patients out of 80. TheMetSpresence rate was 60%. The analysis of the MetS rates in disease groups revealed that the highest rate was in 30 of 39 BAA patients (76.90%). The mean MS criterion count was statistically significantly higher in theBAA group when compared to the CE and CAO groups. A statistically significant difference was determined between the abdominal obesity distributionsin BAA, CE, KAO groups. A statistically significant difference was determined between the MS presence in the BAA, CE, CAO groups. CONCLUSION Certain modifiable stroke risk factors are included in a cluster of risk factors called MetS. Efforts to reduce theMetS parameters could be effective in stroke prevention.