Prevalence of Clinical Malaria in District Khairpur Mir’s Sindh, Pakistan

Aim: To evaluate the frequency of malarial parasites in different seasons at district Khairpur Mir’s, Sindh, Pakistan. Study Design: A prospective study. Place and study duration: This study was conducted at Post Graduate Diagnostic and Research Laboratory (PGRDL), Institute of Microbiology Shah Abdul Latif University (SALU), Khairpur and Bismillah Medical Center (BMC), Khairpur, from 01-Jan-2021 to 30-June-2021. Methodology: Febrile patient of all ages and both sexes were included, pre-diagnosis of malarial parasites using the Immunochromatographic test (ICT) kits, the blood samples were taken by venepuncture procedure after collecting samples in Ethylene diamine tetra acetic acid (EDTA) tubes for ICT and blood slides for microscopy. All results were entered and analyzed in SPSS 24 version. Continuous variables were presented as mean and SD and qualitative variables were presented as frequency/percentages. Probability value ≤0.05 was considered as significant. Results: In this study overall 7332 febrile patients with means age 37.8±22.54, from which male 3476 (47%) and majority of 3856 (53%) were female patients. Whereas 1908 (26%) patients were suffered from the active state of malaria and majority of 5424 (74%) population suffered from non-malarial diseases having vague symptoms including the chills, fever, body aches, abdominal cramps. The positive cases of Plasmodium vivax 1534 (20.92%) Plasmodium falciparum 316 (4%) whereas mixed cases are 58 (1%). Conclusion: The malarial parasites were observed predominantly with type of P. Vivax followed by P. falciparum and mix cases. Therefore dire need to take preventive measures by controlling the spread of plasmodium species in month of March onward till June. Keywords: Malarial Parasites (MP), Febrile Patients, Immunochromatographic Test (ICT).