Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
“Understanding Enterococcus Biofilm: A Path to Targeted Therapy”
View through CrossRef
Abstract: The prevalence of nosocomial infections is escalating due to
the rise of antimicrobial-resistant ESKAPE pathogens, including
Enterococcus species. This review explores the molecular intricacies
governing biofilm formation in Enterococcus, shedding light on its
persistent nature and implications for treatment. The study delves into
genetic determinants, efflux pumps, and metabolic adaptations driving
antibiotic resistance and biofilm resilience. Challenges in current
therapeutic approaches are highlighted, emphasizing the need for
precision medicine tailored to Enterococcus strains. The review presents
emerging therapeutic strategies, including bacteriophage therapy and
engineered nanoparticles. Recent advancements and experimental
treatments, such as quorum sensing manipulation and omics integration,
offer promising avenues for targeted interventions. In conclusion, this
comprehensive review contributes valuable insights for researchers,
clinicians, and policymakers in the ongoing battle against antimicrobial
resistance. Keywords: ESKAPE; Pathogens; Enterococcus; Biofilm;
Antimicrobial resistance
Title: “Understanding Enterococcus Biofilm: A Path to Targeted Therapy”
Description:
Abstract: The prevalence of nosocomial infections is escalating due to
the rise of antimicrobial-resistant ESKAPE pathogens, including
Enterococcus species.
This review explores the molecular intricacies
governing biofilm formation in Enterococcus, shedding light on its
persistent nature and implications for treatment.
The study delves into
genetic determinants, efflux pumps, and metabolic adaptations driving
antibiotic resistance and biofilm resilience.
Challenges in current
therapeutic approaches are highlighted, emphasizing the need for
precision medicine tailored to Enterococcus strains.
The review presents
emerging therapeutic strategies, including bacteriophage therapy and
engineered nanoparticles.
Recent advancements and experimental
treatments, such as quorum sensing manipulation and omics integration,
offer promising avenues for targeted interventions.
In conclusion, this
comprehensive review contributes valuable insights for researchers,
clinicians, and policymakers in the ongoing battle against antimicrobial
resistance.
Keywords: ESKAPE; Pathogens; Enterococcus; Biofilm;
Antimicrobial resistance.
Related Results
Optogenetic Modulation of a Productive Biofilm for Improved Biotransformation
Optogenetic Modulation of a Productive Biofilm for Improved Biotransformation
<p>Biofilm as a living catalysts has been exploited for the production of biofuels and bioelectricity in microbial fuel cells (MFCs) as well as in the synthesis of bu...
Biofilm Producing Enterococcus Isolates from Vaginal Microbiota
Biofilm Producing Enterococcus Isolates from Vaginal Microbiota
Background: Enterococcus is an important cause of infection in the hospital as well as in the community. Methods: A prospective study was done in Medical College, Kolkata for a per...
Biofilm Formation Capabilities of Lactobacillus Species Isolated from Selected Fermented Food Products Using a Statistical Approach
Biofilm Formation Capabilities of Lactobacillus Species Isolated from Selected Fermented Food Products Using a Statistical Approach
Background: This study investigates the biofilm formation capabilities of Lactobacillus species isolated from fermented cassava and corn products. Understanding biofilm formation i...
Evaluation of the antibacterial and anticancer activities of marine Bacillus subtilis ESRAA3010 against different multidrug resistant Enterococci (MDRE) and cancer cell lines
Evaluation of the antibacterial and anticancer activities of marine Bacillus subtilis ESRAA3010 against different multidrug resistant Enterococci (MDRE) and cancer cell lines
Fifty nine isolates belonging to six species of Enterococci namely, Enterococcus faecalis, Enterococcus faecium, Enterococcus raffinosus, Enterococcus durans, Enterococcus mundtiia...
Massively parallel transposon mutagenesis identifies temporally essential genes for biofilm formation inEscherichia coli
Massively parallel transposon mutagenesis identifies temporally essential genes for biofilm formation inEscherichia coli
AbstractBiofilms complete a life cycle where cells aggregate, grow and produce a structured community before dispersing to seed biofilms in new environments. Progression through th...
Biofilm-producing ability of methicillin-resistant Staphylococcus aureus clinically isolated in China
Biofilm-producing ability of methicillin-resistant Staphylococcus aureus clinically isolated in China
Abstract
Background
Staphylococcus aureus, a commensal bacterium, colonizes the skin and mucous membranes of approximately 30% of the human population. Apart from convent...
Lack of defense systems drives Enterococcus easily evolved into lysogens
Lack of defense systems drives Enterococcus easily evolved into lysogens
Abstract
Background: Enterococcus are important opportunistic pathogens that readily acquire foreign genes and could be easily lysogenized by phages. But no comparative gen...
Beyond antibiotics: CRISPR/Cas9 triumph over biofilm-associated antibiotic resistance infections
Beyond antibiotics: CRISPR/Cas9 triumph over biofilm-associated antibiotic resistance infections
A complex structure known as a biofilm is formed when a variety of bacterial colonies or a single type of cell in a group sticks to a surface. The extracellular polymeric compounds...