Search engine for discovering works of Art, research articles, and books related to Art and Culture
ShareThis
Javascript must be enabled to continue!

DIAGNOSTIC EVALUATION OF THE LUPUS BAND TEST IN DISCOID AND SYSTEMIC LUPUS ERYTHEMATOSUS

View through CrossRef
Abstract Background. The usefulness of the lupus band test (lbt) in the diagnosis of cutaneous lupus erythematosus remains controversial. The study was done to determine the sensitivity, specificity, and predictive value of the lbt in discoid lupus erythematosus (dle) and systemic lupus erythematosus (sle). Methods. During the study period, 32 patients with SLE and 28 patients with DLE were included. The final classification of cases was based on the American Rheumatism Association Criteria (ara) for sle, histopathology, and consensus of the clinical staff. Thirty controls, 15 each for DLE and sle, were chosen from a group of patients, who had lesions clinically simulating dle and sle, but could be excluded by histopathology, laboratory tests, and follow‐up. Histopathologic examinations and direct immunofluorescence (DIF) tests were done on lesional skin. Results. In dle, the sensitivity of the LE band test was 58% and the specificity 87%. The positive predictive value was 95% and negative predictive value was 32%. In sle the sensitivity was 93% and specificity 87%. The positive predictive value was 64% and negative predictive value 98%. Conclusions. The high negative predictive value of lbt in sle suggests that it is valuable in excluding diseases clinically similar to sle.
Title: DIAGNOSTIC EVALUATION OF THE LUPUS BAND TEST IN DISCOID AND SYSTEMIC LUPUS ERYTHEMATOSUS
Description:
Abstract Background.
The usefulness of the lupus band test (lbt) in the diagnosis of cutaneous lupus erythematosus remains controversial.
The study was done to determine the sensitivity, specificity, and predictive value of the lbt in discoid lupus erythematosus (dle) and systemic lupus erythematosus (sle).
Methods.
During the study period, 32 patients with SLE and 28 patients with DLE were included.
The final classification of cases was based on the American Rheumatism Association Criteria (ara) for sle, histopathology, and consensus of the clinical staff.
Thirty controls, 15 each for DLE and sle, were chosen from a group of patients, who had lesions clinically simulating dle and sle, but could be excluded by histopathology, laboratory tests, and follow‐up.
Histopathologic examinations and direct immunofluorescence (DIF) tests were done on lesional skin.
Results.
In dle, the sensitivity of the LE band test was 58% and the specificity 87%.
The positive predictive value was 95% and negative predictive value was 32%.
In sle the sensitivity was 93% and specificity 87%.
The positive predictive value was 64% and negative predictive value 98%.
Conclusions.
The high negative predictive value of lbt in sle suggests that it is valuable in excluding diseases clinically similar to sle.

Related Results

Provocative Tests in Diagnosis of Thoracic Outlet Syndrome: A Narrative Review
Provocative Tests in Diagnosis of Thoracic Outlet Syndrome: A Narrative Review
Abstract Thoracic outlet syndrome (TOS) is a group of conditions caused by the compression of the neurovascular bundle within the thoracic outlet. It is classified into three main ...
Precision medicine and patient perspectives in systemic lupus erythematosus
Precision medicine and patient perspectives in systemic lupus erythematosus
<p dir="ltr">Systemic lupus erythematosus (SLE) is an autoimmune disease (AID) with diverse clinical presentations and complex immunopathogenesis. Its chronic and variable co...
Precision medicine and patient perspectives in systemic lupus erythematosus
Precision medicine and patient perspectives in systemic lupus erythematosus
<p dir="ltr">Systemic lupus erythematosus (SLE) is an autoimmune disease (AID) with diverse clinical presentations and complex immunopathogenesis. Its chronic and variable co...
Spontaneous tendon rupture in systemic lupus erythematosus: association with Jaccoud’s arthropathy
Spontaneous tendon rupture in systemic lupus erythematosus: association with Jaccoud’s arthropathy
Tendon rupture has rarely been described in patients with systemic lupus erythematosus. From observation of three cases of Jaccoud’s arthropathy with tendon rupture, and considerin...
Histology of Skin Alterations in Lupus Erythematosus
Histology of Skin Alterations in Lupus Erythematosus
Abstract Lupus erythematosus is an autoimmune connective tissue disorder showing a broad spectrum of clinical manifestations. The a...
Within Tree Distribution of A Discoid Gall on Caryocar Brasiliense (Caryocaraceae)
Within Tree Distribution of A Discoid Gall on Caryocar Brasiliense (Caryocaraceae)
We recorded the discoid gall spatial distribution within Caryocar brasiliense trees in two areas of pasture and one of savanna. A higher num...

Back to Top