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Amniotic Membrane Graft in Ocular Cicatricial Pemphigus: A More Conservative Approach

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Purpose: To report more conservative management of ocular cicatricial pemphigus (OCP) lesions by performing an initial corneal partial amniotic membrane graft without disturbance of the inflamed conjunctiva. Methods: A case report of a patient having a stage 3 OCP in his left eye with a corneal ulcer. He was managed by partial corneal amniotic membrane (AM) graft. Results: The course was favorable with complete corneal ulcer healing and incidentally there was an important regression of associated ocular surface inflammatory signs with a less prominent inferior symblepharon strand. Conclusion: We propose to manage newly diagnosed patients having advanced ocular cicatricial pemphigus disease with partial corneal amniotic membrane graft before performing radical adnexal surgery with prior immunosuppressive treatment.
Title: Amniotic Membrane Graft in Ocular Cicatricial Pemphigus: A More Conservative Approach
Description:
Purpose: To report more conservative management of ocular cicatricial pemphigus (OCP) lesions by performing an initial corneal partial amniotic membrane graft without disturbance of the inflamed conjunctiva.
Methods: A case report of a patient having a stage 3 OCP in his left eye with a corneal ulcer.
He was managed by partial corneal amniotic membrane (AM) graft.
Results: The course was favorable with complete corneal ulcer healing and incidentally there was an important regression of associated ocular surface inflammatory signs with a less prominent inferior symblepharon strand.
Conclusion: We propose to manage newly diagnosed patients having advanced ocular cicatricial pemphigus disease with partial corneal amniotic membrane graft before performing radical adnexal surgery with prior immunosuppressive treatment.

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