The Changes of Serum Lipids in Idiopathic Epiretinal Macular Membranes

Abstract Purpose: To describe the changes of serum lipids in patients with idiopathic epiretinal macular membranes (iERMs). Methods: A retrospective, observational case control study was performed January 2015 and December 2019 in our unit. A total of 57 subjects with idiopathic epiretinal macular membranes were collected in the study. Senile cataract patients with age matched during hospitalizations were randomly collected as control group. iERMs were diagnosed based on OCT images. Comprehensive ophthalmologic examinations and Systemic examinations were performed. The changes of serum lipids were analyzed. Results: The iERMs was common in female (71.9%). Compared to control group, Serum triglycerides were higher in iERMs group (1.54 ± 0.66 vs 1.21 ± 0.50, P < 0.01). There was significant difference in BMI with iERM (23.68 ± 2.86 vs 22.50 ± 2.71, P = 0.03). After subjects stratified according whether with hypertension diseases, there was still statistical difference in serum triglycerides (P < 0.05). Conclusions: Serum triglycerides and BMI are elevated in patients with iERMs. It suggests that obese people seem to be prone to iERMs. Hyperlipemia seems to play a role in the formation of iERMs.