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A life-threatening complication due to pulmonary haemorrhage following hump-nosed viper bite

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Abstract Background Hump-nosed viper bite, the commonest venomous snake bite in Sri Lanka, is associated with significant morbidity. Specific anti-venom is not available for hump-nosed viper envenomation which is usually managed with supportive treatment. Pulmonary haemorrhage is an unusual manifestation of hump-nosed viper bite. Here we present a case of hump-nosed viper envenomation which complicated by pulmonary haemorrhage and was successfully treated with systemic steroids. To the best of our knowledge, it has not been reported in the literature before. Case presentation A previously healthy 55-year-old man presented to the local hospital 18 h after a hump-nosed viper bite. He developed bilateral severe pulmonary haemorrhages, evidenced by rapid desaturation which needed intubation and mechanical ventilation, bleeding from the endotracheal tube and bilateral alveolar shadows in a chest x-ray. He had no other bleeding manifestations. Because of the life-threatening situation, he was treated with methylprednisolone pulse therapy. There was a rapid improvement of hypoxia with a resolution of x-ray changes. He was successfully weaned off from the ventilation after 24 h. Conclusion This case highlights the importance of suspecting pulmonary haemorrhage in a patient who develops desaturation and alveolar shadow following hump-nosed viper bite even in the absence of other bleeding manifestation. Early and timely treatment with systemic steroid can be lifesaving in such patients.
Title: A life-threatening complication due to pulmonary haemorrhage following hump-nosed viper bite
Description:
Abstract Background Hump-nosed viper bite, the commonest venomous snake bite in Sri Lanka, is associated with significant morbidity.
Specific anti-venom is not available for hump-nosed viper envenomation which is usually managed with supportive treatment.
Pulmonary haemorrhage is an unusual manifestation of hump-nosed viper bite.
Here we present a case of hump-nosed viper envenomation which complicated by pulmonary haemorrhage and was successfully treated with systemic steroids.
To the best of our knowledge, it has not been reported in the literature before.
Case presentation A previously healthy 55-year-old man presented to the local hospital 18 h after a hump-nosed viper bite.
He developed bilateral severe pulmonary haemorrhages, evidenced by rapid desaturation which needed intubation and mechanical ventilation, bleeding from the endotracheal tube and bilateral alveolar shadows in a chest x-ray.
He had no other bleeding manifestations.
Because of the life-threatening situation, he was treated with methylprednisolone pulse therapy.
There was a rapid improvement of hypoxia with a resolution of x-ray changes.
He was successfully weaned off from the ventilation after 24 h.
Conclusion This case highlights the importance of suspecting pulmonary haemorrhage in a patient who develops desaturation and alveolar shadow following hump-nosed viper bite even in the absence of other bleeding manifestation.
Early and timely treatment with systemic steroid can be lifesaving in such patients.

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