Supplementary Figures 1 - 11 from An Inducible Hepatocellular Carcinoma Model for Preclinical Evaluation of Antiangiogenic Therapy in Adult Mice

<p>PDF file - 8221K, Supplementary Figure S1: Kinetics of tumorigenic transformation, Supplementary Figure S2: Kinetics of VEGF expression. Supplementary Figure S3: Functional liver tumor vasculature. Supplementary Figure S4: Side effects in long-term Sorafenib-treated iAST mice. Supplementary Figure S5: VEGF-A expression after Sorafenib treatment Supplementary Figure S6: Necrosis and hypoxia in Sorafenib-treated livers. Supplementary Figure S7: Sinusoidal marker expression upon Sorafenib treatment. Supplementary Figure S8: Vascular remodeling upon Sorafenib treatment. Supplementary Figure S9: Microarray data analysis. Supplementary Figure S10: Regained proliferative potential after LT-Sorafenib administration. Supplementary Figure S11: Stable weight in Sorafenib-treated mice.</p>