Biopolymer Mechanism: Pharmacokinetics and Pharmacodynamics

Biopolymers have become apparent as a potential therapeutic material, which shows an important role in treating different diseases like cancer, neurological disorders, cardiovascular disorders, infectious diseases, diabetes, and drug delivery. Due to its biocompatible and biodegradable properties, it is widely used for therapeutic purposes. This chapter provides detailed information regarding the pharmacokinetic and pharmacodynamic properties of biopolymers. It involves a comprehensive analysis of how these materials are involved in drug absorption, distribution, metabolism, excretion, and their interaction with physiological systems. The pharmacokinetic properties of biopolymers depend on various factors such as molecular weight, degradation behavior, and structure of biopolymers, which are important for therapeutic efficacy. On the other hand, pharmacodynamic properties provide detailed information regarding mechanisms like cellular uptake and internalization, modulation in immunological responses, and physical and chemical interactions by which these materials show therapeutic responses by targeting specific cells or tissues, extending beyond the target consequences, and receptor-associated interactions. Recent advancements in the field of biopolymers involve their utilization for specific therapeutic effects, enhancing patient compliance and outcomes, with various mechanisms of action involved for showing therapeutic responses by biopolymers mentioned in this chapter. By gathering information regarding biopolymers' pharmacokinetic and pharmacodynamic properties, this chapter aims to provide detailed information on various mechanisms involving the effectiveness and efficacy of biopolymer-based therapeutics in clinical utilization.