Iatrogenic pseudoaneurysms in multicentric Castleman disease – a case for caution

Abstract Background: Castleman disease is a rare, complex lymphoproliferative disorder that is characterized by unicentric or multicentric involvement. Multicentric Castleman disease can be rarely associated with vasculopathy. Case Presentation: While pseudoaneurysm is an uncommon complication of arterial access, we present a case of iatrogenic common femoral artery pseudoaneurysm followed by iatrogenic radial artery pseudoaneurysm after obtaining arterial accesses for interventions in a patient with Castleman disease. Conclusion: Patients with Castleman disease may be at increased risk of developing iatrogenic pseudoaneurysms at arterial access sites. Follow-up ultrasound should be considered after arterial access to assess for pseudoaneurysm formation.