Dental complications due to the use of bisphosphonates

Objective: The main objective of this article is to describe dental complications due to the use of bisphosphonates through a bibliographic review. In turn, this objective had the following specific objectives: a) Identify the treatments in patients administered bisphosphonates, and b) Know the types of bisphosphonates most used associated with dental complications. Materials and methods: This research uses a qualitative approach, which developing through documentary-type research to describe the points raised in the objectives. A systematic review carrying out applying the PRISMA methodology, where the Scopus and PubMed databases using to search for the information in documents published between January 1, 2018 and January 31, 2023 to select the appropriate ones according to inclusion and exclusion criteria. Results: From 11897 initially identified articles, only nine articles met all the eligibility criteria for this study. The selected articles are of high impact belonging to journals within quartiles 1 and 2. Among the most outstanding findings is that the use of antiresorptive therapies with bisphosphonates cause dental complications such as osteonecrosis of the jaw and risks in cases of dental extractions. In addition, the most widely used type of bisphosphonate is zoledronate, the major cause of osteonecrosis of the jaw. Conclusions: Antiresorptive therapies with the use of bisphosphonates, especially with the administration of zoledronate, are the main causes of osteonecrosis of the jaw