Enchondroma Protuberans of the Hand: A Rare Cartilaginous Tumor

Introduction: Enchondroma protuberans (EP), a rare form of enchondroma with exophytic growth, differs radiographically from classical enchondromas and can mimic osteochondroma, periosteal chondroma, or chondrosarcoma. Proper differentiation is crucial to avoid unnecessary radical resection, as EP requires intralesional curettage rather than the surgical removal typical for osteochondromas. Case Report: A 14-year-old male presented with a progressively enlarging, painless mass on the lateral aspect of his left hand, initially noticed 4 years ago. Imaging and biopsy suggested osteochondroma, but histopathology confirmed enchondroma. Post-surgical excision and curettage, the patient reported no pain or limited range of motion at the 4-week follow-up. Conclusion: Accurate diagnosis and differentiation of EP, supported by detailed radiographic and histopathological evaluation, are crucial for timely surgical intervention to prevent malignant transformation and recurrence, highlighting the need for clinical awareness and precise diagnostic protocols. Keywords: Enchondroma, hand, cartilaginous, ollier’s disease.